Article

Cancer in Older Persons: An International Issue in an Aging World

Geriatrics and Clinical Gerontology Program, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892-9205, USA.
Seminars in Oncology (Impact Factor: 3.94). 05/2004; 31(2):128-36. DOI: 10.1053/j.seminoncol.2003.12.024
Source: PubMed

ABSTRACT Persons age 65 years and older bear the greater burden of cancer in the United States and other industrial nations. A cross-national perspective using data from several population-based resources (eg, the NCI Surveillance, Epidemiology, and End Results Program; US Bureau of Census; World Health Organization; and International Association for Research on Cancer) illustrates current and future demographic transitions in America in comparison with six industrial nations, and profiles cancer mortality in older persons across the selected nations--Denmark, France, Italy, Japan, Sweden, and United Kingdom. Mortality rates, age-standardized to the world population, are presented for major tumors. US aging and cancer profiles are highlighted. Demographic projections portend a substantial increase in numbers of older persons, and thus, imply resultant increases in cancer incidence and mortality in the elderly. By 2030, there will be larger proportions of persons in the age group most vulnerable to cancer. Information is needed on how age-related health problems affect cancer prevention, detection, prognosis, and treatment. A knowledge base as guidance in management of cancer in the elderly is lacking. Planning for effective prevention measures and improvement of treatment for the elderly is imperative to meet current and future quality cancer care needs.

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    • "Though studies have identified barriers and raised awareness of issues faced by patients with advanced cancer and their caregivers, there is relatively little understanding of how pain is managed from the dyadic perspectives of older patients and their caregivers within the home setting. The higher prevalence of cancer in old age [6], increased risk for under-treatment of pain [7,8], and complexity associated with pain management in this population [9,10], calls attention to the need to identify and address the unique needs of these patients and their caregivers. Consequently, the purpose of this study was to describe the roles and perceptions of older patients with advanced cancer and their caregivers in managing pain in the home setting. "
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    South Asian Journal of Cancer 10/2013; 2(4):202-8. DOI:10.4103/2278-330X.119904
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    • "Cancer incidence increases with advancing age, which is a concerning fact in most Western countries where life expectancy is increasing and the elderly population is expanding [1]. The relationship between cancer and aging is not fully understood, although the natural passing of time may allow the accumulation of damage from free radicals, viruses, and carcinogens to cause mutated cellular proliferation that disrupts normal physiology and facilitates cancer development. "
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