Article
A prospective study of Fel d1 and Der p1 exposure in infancy and childhood wheezing.
Unitat Recerca Respiratòria i Ambietal, Institut Municipal Investigació Mèdica, Barcelona, Spain.
American Journal of Respiratory and Critical Care Medicine (impact factor:
11.08).
09/2004;
170(3):273-8.
DOI:10.1164/rccm.200310-1348OC
Source: PubMed
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Citations (0)
- Cited In (15)
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Article: Environmental assessment and exposure control: a practice parameter--furry animals.
Annals of allergy, asthma & immunology: official publication of the American College of Allergy, Asthma, & Immunology 04/2012; 108(4):223.e1-15. · 2.83 Impact Factor -
Article: Perinatal cat and dog exposure and the risk of asthma and allergy in the urban environment: a systematic review of longitudinal studies.
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ABSTRACT: The literature is contradictory concerning pet exposure and the risk of development of asthma and other allergic diseases. Using longitudinal studies, we aimed to systematically review the impact of pet ownership in the critical perinatal period as a risk factor for allergies in childhood. Medline database was searched for urban cohort studies with perinatal exposure to cats and/or dogs and subsequent asthma or allergic disease. Nine articles, comprising 6498 participants, met inclusion criteria. Six found a reduction in allergic disease associated with perinatal exposure to dogs or, cats or dogs. One study found no association. Two found increased risk only in high-risk groups. Longitudinal studies in urban populations suggest that perinatal pets, especially dogs, may reduce the development of allergic disease in those without a family history of allergy. Other unmeasured factors such as pet-keeping choices in allergic families may be confounding the association seen in these high-risk families, and further study is required.Clinical and Developmental Immunology 01/2012; 2012:176484. · 1.84 Impact Factor -
Article: Effect of cat and daycare exposures on the risk of asthma in children with atopic dermatitis.
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ABSTRACT: Atopic dermatitis (AD) in young children is often followed by the development of asthma (atopic march). The role of environmental exposures is unclear in this high-risk population. We aimed to determine the predictive relationship between indoor allergen exposures, particularly pets, rodents, and cockroaches, to the development of asthma in a prospective pediatric cohort. Children with AD and a family history of allergy were followed prospectively with questionnaire ascertainment of environmental exposure to cats, dogs, cockroaches, rats, and mice. Asthma was diagnosed by study physicians based on caregiver reports of symptoms continually assessed over the course of the study period. Fifty-five of the 299 children developed asthma by the end of the study. Cat exposure had a strong and independent effect to reduce the risk of developing asthma across all analyses (odds ratio [OR], 0.16; 95% confidence interval [CI], 0.05-0.53). Dog, mouse, rat, and cockroach exposures did not significantly influence the development of asthma. Daycare exposure had the largest risk reduction for the development of asthma (OR, 0.08; 95% CI, 0.03-0.19). Maternal asthma (OR, 2.93; 95% CI, 1.29-6.67), baseline body mass index (OR, 1.23; 95% CI, 1.08-1.42), and specific immunoglobulin E to house-dust mix at 3 years were each independent risk factors for the development of asthma. In children with AD, cat and daycare exposure may reduce the risk of developing early childhood asthma.Allergy and Asthma Proceedings 05/2012; 33(3):282-8. · 2.17 Impact Factor
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Keywords
1-year-olds
4 years
95% confidence interval
cat allergen
complete outcome data
data support
different risk profiles
Distinct risk profiles
Domestic allergen levels varied
domestic exposure
dust sample collection
Fel d1 exposure varied
first 4 years
first year
house dust mite
maternal asthma
multicenter prospective birth cohort
Multivariate analysis
relative risk
Year 4
