Second Malignant Neoplasms following Hematopoietic Stem Cell Transplantation

University of Washington, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
International Journal of Hematology (Impact Factor: 1.92). 05/2004; 79(3):229-34. DOI: 10.1532/IJH97.03178
Source: PubMed


Hematopoietic stem cell transplantation is being successfully used to treat a variety of malignant and nonmalignant disorders. This therapy has resulted in an increasing number of survivors who are at risk for adverse long-term outcomes, including the development of second and subsequent malignant neoplasms. We review the incidence and spectrum of posttransplantation malignancies and discuss risk factors and future directions for research.

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