Citalopram and mania
Available from: Ayse Kilincaslan
- "Escitalopram induced mania has been reported in an adult with unipolar depressive disorder (Prapotnik et al. 2004). Also Pravin et al. (2004) described an adolescent with severe major depression and a family history of depression who developed mania with concomitant use of citalopram and escitalopram. But a recent study that examined the efficiency and safety of escitalopram (10–20 mg/day) in children and adolescents with depression revealed one patient with manic reaction treated with placebo but none with escitalopram (Wagner et al. 2006). "
Journal of Child and Adolescent Psychopharmacology 03/2008; 18(1):119-20. DOI:10.1089/cap.2007.0099 · 2.93 Impact Factor
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ABSTRACT: There has been much recent attention on the adverse effects of serotonin reuptake inhibitors on children and adolescents. One well-known adverse effect of antidepressants in adults is manic induction. Our group recently used an administrative database to study the effects of age on antidepressant-induced manic conversion and found that peri-pubertal children may be most vulnerable to manic induction. This review will address the following questions: (1) What is known about antidepressant-induced mania and rapid cycling in children and adolescents? (2) Could antidepressant exposure in children and adolescents lead to long-term mood destabilization?; and finally, (3) What research and clinical recommendations can be made based on what is known thus far?
International Review of Neurobiology 02/2005; 65:25-52. DOI:10.1016/S0074-7742(04)65002-1 · 1.92 Impact Factor
Side Effects of Drugs Annual 01/2008; 30. DOI:10.1016/S0378-6080(08)00002-0
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