Prevalence and factor analysis of metabolic syndrome in an urban Korean population.
ABSTRACT The aim of this study was to explore the prevalence and pattern of the metabolic syndrome and its association with hyperinsulinemia in an urban Korean population of 269 men and 505 women.
The National Cholesterol Education Program Adult Treatment Panel (ATP) III guidelines were used to calculate the sex-specific prevalence of the metabolic syndrome. After excluding individuals taking medication for hypertension, diabetes, or dyslipidemia, we used factor analysis to examine the pattern of the metabolic syndrome in 206 men and 449 women.
The prevalence of metabolic syndrome was 16.0% in men and 10.7% in women aged 30-80 years. However, ATP III criteria for central obesity are not optimal for an Asian-Pacific population; when waist circumference is reduced from 102 to 90 cm in men and 88 to 80 cm in women, the prevalence of the metabolic syndrome increased to 29.0 and 16.8%, respectively. Sex-specific factor analysis showed four factors in men (obesity, glucose intolerance, hypertension, and dyslipidemia) and three in women (obesity-hypertension, glucose intolerance, and obesity-dyslipidemia). Insulin resistance estimated from fasting insulin levels clustered with three of the four factors in men and two of the three factors in women. By ATP III or Asian-Pacific waist circumference criteria, the prevalence of the metabolic syndrome increased with increasing tertiles of insulin resistance, which was estimated by a homeostasis model assessment.
The metabolic syndrome is common in an urban Korean population when using Asian-Pacific waist criteria. The prevalence of the metabolic syndrome increased with increasing tertiles of insulin resistance.
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ABSTRACT: Non-alcoholic fatty liver disease (NAFLD) isa manifestation of metabolic syndromelargely confined to residents of affluentindustrialized Western countries. Nonalcoholicsteatohepatitis (NASH) is a criticallink in the chain of metabolic fatty liverdisorders that spans steatosis to cryptogeniccirrhosis. The increasing prevalence ofobesity, coupled with diabetes, dyslipidemia,hypertension and the ultimate upsurge inmetabolic syndrome in the Asia-Pacificregion, puts a very large population at risk ofdeveloping NAFLD in the coming decades.The review focuses on the emergingproblem of NAFLD in the Indian and Asia-Pacific region, the risk factors and settings inAsians, the cliniocopathological profile andnatural history and highlights its differencefrom the west. Given the scope of theproblem, efforts should focus primarily onpreventing or ameliorating the impact of riskfactors. The simultaneous identification andappropriate treatment of the components ofmetabolic syndrome are crucial to reducehepatic as well as cardiovascular morbidityand mortality.Calicut Medical Journal. 01/2008;
Chapter: Cardiometabolic Syndrome03/2012; , ISBN: 978-953-51-0240-3
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ABSTRACT: Determining metabolic syndrome (MS) prevalence amongst employees from a steel company in Distrito Federal according to age and ethnic-racial classification, comparing biochemical, anthropometric and hemodynamic indicators according to MS presence or absence. A total of 125 men (aged 20-69) participated in the study. Data was collected regarding age, ethnic origin, body weight, height, body mass index (BMI), waist circumference, glucose, triglycerides, total cholesterol, high-density lipoprotein (HDL-c), systolic (SBP) and diastolic blood pressure (DBP). MS prevalence was 28 %. Subjects suffering from MS presented higher triglyceride levels, had greater BMI, waist circumference, SBP and DBP and lower HDL-c. Increased MS frequency was observed with age, having higher frequency (45.9 %) amongst subjects aged more than 40. MS prevalence was high amongst steel company workers; the condition was associated with age.Revista de salud publica (Bogota, Colombia) 08/2010; 12(4):635-46.