Article

ICA69 autoantibodies in primary Sjögren's syndrome.

Lupus (impact factor: 2.34). 02/2004; 13(6):483-4. pp.483-4
Source: PubMed
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    Article: Sjögren's syndrome: studying the disease in mice.
    Nicolas Delaleu, Cuong Q Nguyen, Ammon B Peck, Roland Jonsson
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    ABSTRACT: Sjögren's syndrome (SS), a systemic autoimmune disease, is characterized by inflammation of exocrine tissues accompanied by a significant loss of their secretory function. Clinical symptoms develop late and there are no diagnostic tests enabling early diagnosis of SS. Thus, particularly to study these covert stages, researchers turn to studying animal models where mice provide great freedom for genetic manipulation and testing the effect of experimental intervention. The present review summarizes current literature pertaining to both spontaneous and extrinsic-factor induced SS-like diseases in mouse models, discussing advantages and disadvantages related to the use of murine models in SS research.
    Arthritis research & therapy 06/2011; 13(3):217. · 4.27 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

T P Gordon