Inner Mongolia, China, is an area with high levels of arsenic. The adverse health effects resulting from chronic arsenic exposure include skin keratosis, vascular diseases and cancers. However, the effects of arsenic exposure on mental health have not received much attention. The purpose of this study was to examine the effects of arsenic poisoning on the mental health of the inhabitants of an arsenic-affected area. We performed a cross-sectional study at two villages in Hetao Plain, Inner Mongolia. The populations of both villages were similar in age, sex, lifestyle, socioeconomic conditions, and geographic location. One hundred and thirty four (93.7%) of the 143 inhabitants in the arsenic-affected village and 36 (76.6%) of the 47 inhabitants in the arsenic-free village participated in the study. Subjects with a 30-item version of General Health Questionnaire score of 9 or more were defined as having symptoms of distress. The multiple logistic analyses showed that the mental health of the subjects in the arsenic-affected village was worse than in those in the arsenic-free village (OR=2.5, 95% CI=1.1-6.0). The effect of arsenic on mental health in arsenic-affected areas deserves further investigation. The mental health burden in arsenic-affected areas should be considered in the wider context of public and community health.
"The control of arsenic concentration is of special interest because chronical exposure to excessive arsenic concentration can cause many health problems. If consumed, water with high arsenic concentration can increase the risk toward skin and bladder cancer, as well as kidney and lung cancer (Fatmi et al., 2009; Fujino et al., 2004). The presence of arsenic in water does not affect the smell and the taste of water and geological presence of arsenic doesn't necessarily mean that arsenic will be present in drinking water. "
[Show abstract][Hide abstract] ABSTRACT: Analysis and monitoring of arsenic is still a challenging analytical task. Due to its complex behaviour (different forms of arsenic that can be present depending on pH and oxidation states of arsenic) as well as demanding analytical procedures and instrumental tools for control of arsenic concentration in drinking water which is set to 10 mu g L-1, there are still some open questions and issues when arsenic is the scientific topic. In this paper the idea was to use a multivariate statistical approach to identify the key variables and their relation to high arsenic concentration in surface waters of Serbia. The main idea was to identify and connect the key water quality parameters with arsenic concentration and to suggest adequate treatment technologies for water purification and arsenic removal. The data set for multivariate statistical approach were water quality parameters of surface water samples from Serbia. The artificial neural network (ANN) was applied for data analysis. After applying ANN the results showed strong relation between arsenic concentration and P-tot, SO42-, COD, carbonate, N-org, DO, and SiO2 content. What could be concluded from the obtained results is that high concentration of organic matter, proportional to nutrients (nitrogen and phosphorus), silica (SiO2) and dissolved oxygen highly correlates with the dissolved arsenic which implies that the most adequate technology for the water treatment could be precipitation, which in general includes coagulation. What remains unquestioned and needs to be performed is arsenic speciation analysis.
"Medium Children (6-7 y.o.) ↓capacity in vocabulary Roy et al. 2011  Low and High Children (5-15 y.o.) ↓capacity in vocabulary, language Von Ehrenstein et al. 2007  Low Adults ↓capacity in executive function, mental acuity, verbal skills O'Bryant et al. 2011 [43@BULLET@BULLET] Visual perception Medium Children (6-7 y.o.) ↓capacity in visual search Rosado et al. 2007  Low and High Children (5-15 y.o.) ↓capacity in picture completion, object assembly Von Ehrenstein et al. 2007  Mental health Medium Children ↑risk for ADHD Roy et al. 2011  Low Adults ↑incidence of depression Zierold et al. 2004  Medium Adults ↑symptoms of anxiety Dang et al. 2008 , Dang et al. 2009 Low → High Adults ↓quality of life and mental health Syed et al. 2012  High Adults ↑symptoms of altered mental health Fujino et al. 2004  Low → High Adults ↑insomnia ↓general health Guo et al. 2007  Low → High Adults ↑risk of psychiatric disorder, depression, anxiety Sen et al. 2012  Exposure Low: less than 50 μg/L (ppb) urinary arsenic or water arsenic Medium: between 50 μg/L (ppb) and 100 μg/L (ppb) urinary or water arsenic High: more than 100 μg/L (ppb) urinary arsenic or water arsenic with other factors that could affect the outcomes of these studies (Table 2). These include exposures to a mixture of metals, low socioeconomic status, and poor nutrition. "
[Show abstract][Hide abstract] ABSTRACT: Arsenic toxicity is a worldwide health concern as several millions of people are exposed to this toxicant via drinking water, and exposure affects almost every organ system in the body including the brain. Recent studies have shown that even low concentrations of arsenic impair neurological function, particularly in children. This review will focus on the current epidemiological evidence of arsenic neurotoxicity in children and adults, with emphasis on cognitive dysfunction, including learning and memory deficits and mood disorders. We provide a cohesive synthesis of the animal studies that have focused on neural mechanisms of dysfunction after arsenic exposure including altered epigenetics; hippocampal function; glucocorticoid and hypothalamus-pituitary-adrenal axis (HPA) pathway signaling; glutamatergic, cholinergic and monoaminergic signaling; adult neurogenesis; and increased Alzheimer’s-associated pathologies. Finally, we briefly discuss new studies focusing on therapeutic strategies to combat arsenic toxicity including the use of selenium and zinc.
". Furthermore, a cross-sectional study in two villages in Inner Mongolia, China found that the mental health of the subjects in the arsenic-affected village was worse than in those in the arsenic-free village (OR= 2.5, 95% CI=1.1.–6.0) . In addition, experiences with animals have pointed out that perinatal arsenic exposure was associated with depressive-like behaviors in the affected mouse offspring . "
[Show abstract][Hide abstract] ABSTRACT: Underground water in many regions of the world is contaminated with high concentrations of arsenic and the resulting toxicity has created a major environmental and public health problem in the affected regions. Chronic arsenic exposure can cause many diseases, including various physical and psychological harms. Although the physical problems caused by arsenic toxicity are well reported in literature, unfortunately the consequences of arsenic exposure on mental health are not adequately studied. Therefore we conducted a review of the available literature focusing on the social consequences and detrimental effects of arsenic toxicity on mental health. Chronic arsenic exposures have serious implications for its victims (i.e. arsenicosis patients) and their families including social instability, social discrimination, refusal of victims by community and families, and marriage-related problems. Some studies conducted in arsenic affected areas revealed that arsenic exposures are associated with various neurologic problems. Chronic arsenic exposure can lead to mental retardation and developmental disabilities such as physical, cognitive, psychological, sensory and speech impairments. As health is defined by the World Health Organization as "a state of complete physical, mental and social wellbeing", the social dimensions have a large impact on individual's mental health. Furthermore studies in China und Bangladesh have shown that mental health problems (e.g. depression) are more common among the people affected by arsenic contamination. Our study indicates various neurological, mental and social consequences among arsenic affected victims. Further studies are recommended in arsenic-affected areas to understand the underlying mechanisms of poor mental health caused by arsenic exposure.
International Journal of Environmental Research and Public Health 06/2009; 6(5):1609-19. DOI:10.3390/ijerph6051609 · 2.06 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.