Article

A simple and highly efficient P,O-type ligand for Suzuki-Miyaura cross-coupling of aryl halides.

Open Laboratory of Chirotechnology of the Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong.
Chemical Communications (Impact Factor: 6.38). 10/2004; DOI: 10.1039/b407243j
Source: PubMed

ABSTRACT A simple and efficient hemilabile-type phosphine ligand, found to be highly effective in Suzuki-Miyaura cross-coupling of aryl chlorides with generally low Pd-catalyst loading (0.05%), was prepared in one step based on an economically attractive approach from commercially available benzamide starting material.

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