A Simple and Highly Efficient P,O-Type Ligand for Suzuki?Miyaura Cross-Coupling of Aryl Halides.

Department of Chemistry, The Chinese University of Hong Kong, Hong Kong, 00, Hong Kong
Chemical Communications (Impact Factor: 6.83). 10/2004; 36(17):1922-3. DOI: 10.1039/b407243j
Source: PubMed


A simple and efficient hemilabile-type phosphine ligand, found to be highly effective in Suzuki-Miyaura cross-coupling of aryl chlorides with generally low Pd-catalyst loading (0.05%), was prepared in one step based on an economically attractive approach from commercially available benzamide starting material.

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