Article
Protective effect of the in situ formed short-term salivary pellicle.
Clinic of Operative Dentistry, Periodontology and Preventive Dentistry, Saarland University Hospitals, Building 73, D-66421 Homburg/Saar, Germany.
Archives of Oral Biology (impact factor:
1.6).
11/2004;
49(11):903-10.
DOI:10.1016/j.archoralbio.2004.05.008
Source: PubMed
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Citations (0)
- Cited In (7)
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Article: Effect of Psidium cattleianum leaf extract on enamel demineralisation and dental biofilm composition in situ.
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ABSTRACT: Previous evaluations of Psidium cattleianum leaf extract were not done in conditions similar to the oral environment. The aim of this study was to evaluate the effect of P. cattleianum leaf extract on enamel demineralisation, extracellular polysaccharide formation, and the microbial composition of dental biofilms formed in situ. Ten volunteers took part in this crossover study. They wore palatal appliances containing 4 enamel blocks for 14 days. Each volunteer dripped 20% sucrose 8 times per day on the enamel blocks. Twice a day, deionised water (negative control), extract, or a commercial mouthwash (active control) was dripped after sucrose application. On the 12th and 13th days of the experiment, plaque acidogenicity was measured with a microelectrode, and the pH drop was calculated. On the 14th day, biofilms were harvested and total anaerobic microorganisms (TM), total streptococci (TS), mutans streptococci (MS), and extracellular polysaccharides (EPS) were evaluated. Enamel demineralisation was evaluated by the percentage change of surface microhardness (%ΔSMH) and integrated loss of subsurface hardness (ΔKHN). The researcher was blinded to the treatments during data collection. The extract group showed lower TM, TS, MS, EPS, %ΔSMH, and ΔKHN values than the negative control group. There were no differences between the active and negative control groups regarding MS and EPS levels. There were no differences in pH drop between the extract and active control groups, although they were significantly different from the negative control group. For all other parameters, the extract differed from the active control group. Psidium cattleianum leaf extract exhibits a potential anticariogenic effect.Archives of oral biology 03/2012; 57(8):1034-40. · 1.65 Impact Factor -
Article: Dental erosion as oral disease. Insights in etiological factors and pathomechanisms, and current strategies for prevention and therapy.
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ABSTRACT: Dental erosion is induced by the exposure to acids, and together with physical impacts, contributes to the wear and tear of the dentition throughout a lifetime. It is a multifactorial condition, and so far several etiological and protecting factors have been identified. Based on a thorough diagnosis and identification of the acid sources, current preventive and therapeutic strategies focus on causal strategies bringing the acid exposure to a safe level, and/or strengthening the tooth surface against demineralization. There is increasing knowledge about the erosion inhibiting potential of fluorides particularly of compounds with polyvalent metal cations. The paper critically reviews the current literature providing a brief overview on what is known about diagnosis, prevalence, etiology and risk factors with the main focus on preventive and therapeutic strategies.American journal of dentistry 12/2012; 25(6):351-64. · 0.76 Impact Factor -
Article: A new optical detection method to assess the erosion inhibition by in vitro salivary pellicle layer.
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ABSTRACT: OBJECTIVES: Application of the recently developed optical method based on the monitoring of the specular reflection intensity to study the protective potential of the salivary pellicle layer against early enamel erosion. METHODS: The erosion progression was compared between two treatment groups: enamel samples coated by the 15h-in vitro-formed salivary pellicle layer (group P, n=90) and the non-coated enamel surfaces (control group C, n=90). Different severity of the erosive impact was modelled by the enamel incubation in 1% citric acid (pH=3.6) for 2, 4, 8, 10 or 15min. Erosion quantification was performed by the optical method as well as by the microhardness and calcium release analyses. RESULTS: Optical assessment of the erosion progression showed erosion inhibition by the in vitro salivary pellicle in short term acidic treatments (≤4min) which was also confirmed by microhardness measurements proving significantly less (p<0.05) enamel softening in the group P at 2 and 4min of erosion compared to the group C. SEM images demonstrated less etched enamel interfaces in the group P at short erosion durations as well. CONCLUSIONS: Monitoring of the specular reflection intensity can be successfully applied to quantify early erosion progression in comparative studies. In vitro salivary pellicle (2h) provides erosion inhibition but only in short term acidic exposures. CLINICAL SIGNIFICANCE: The proposed optical technique is a promising tool for the fast and non-invasive erosion quantification in clinical studies.Journal of dentistry 02/2013; · 2.00 Impact Factor
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Keywords
120 min pellicle
3 min pellicle
60 min pellicle
average microhardness loss values
Calcium release values
certain processes
enamel surface area
erosive action
erosive alterations
maxillary first molars
microhardness loss 187.0 DeltaKHN
micromorphological examination
morphologic alterations
pellicle formation time
pellicle-covered surfaces
protective effect
salivary pellicle
scanning electron microscope
short-term salivary pellicle
significant protection
