Article

[The expression of nm23-H1 in the investing papilloma and it's cancerated tissue of nasal cavity and parasinuses].

Department of Otorhinolaryngology, the First Affiliated Hospital of Sun-Yat-Sen University, Guangzhou, 510080, China.
Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 02/2004; 18(2):86-7. pp.86-7
Source: PubMed

ABSTRACT To investigate the role of the nm23-H1 protein in the development of investing papilloma and it's cancerated tissue in nasal cavity and parasinuses.
The expression of nm23-H1 protein was measured by immunohistochemistry in twenty-five cases with investing papilloma and twenty-one cases with cancerated investing papilloma in nasal cavity and parasinuses and fourteen cases with chronic sinusitis.
The expression of nm23-H1 in the investing papilloma was higher than that in cancerated investing papilloma tissue, the positive rate was 72% and 42% respectively in the two groups, P < 0.05. The expression of nm23-H1 in the investing papilloma was higher than in the chronic sinusitis, the positive rate of the latter was 14.3%, P < 0.05.
The lower expression the nm23-H1 protein in the cancerated tissue of investing papilloma was related to the infiltration and canceration.

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