The septum pellucidum and its variants. An MRI study.
ABSTRACT Increased prevalence of cavum septi pellucidi (CSP) in schizophrenic patients in comparison to healthy subjects was reported previously. Our purpose was to evaluate the prevalence of variants of the septum pellucidum in healthy subjects in three different age groups.
151 healthy subjects, including 46 children (age 6 +/- 4 years), 72 young adults (age 31 +/- 8 years) and 33 elderly adults (age 59 +/- 7 years) were examined with high-resolution MRI. Three observers analysed the images using a standardised protocol. We evaluated the incidences of CSP, cavum vergae (CV) and their length.
CSP was detected in 80% of the cases in the paediatric group and 68% of young adults and in 72% of the elderly adults. A cavum vergae (CV) was noted in 22% of the children, in 39% of the young adults and in 36% of the elderly subjects. There was no significant difference between the age-related groups.
We detected a high prevalence of cavum septi pellucidi without a significant age dependence. Enlarged cava septi pellucidi are rare in healthy subjects.
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ABSTRACT: Corpus callosum (CC) might be related to cognitive performance because of its role in interhemispheric communication. Previous research has focused mainly on volumetric analyses of the CC, yielding contradictory results to some extent. Shape is an approach that integrates and extends the data obtained with the volumetric methodology. Here, we analyze the relationships between midsagittal CC shape variation and several cognitive measures. 2D coordinates from 102 MRI-scanned young adult human CCs were superimposed through a Procrustes approach. The residual variation was regressed onto 21 cognitive measures completed by the participants. Most of these measures (including general intelligence, working memory, executive functioning, and mental speed) were unrelated to midsagittal CC morphology. However, attentional control did show consistent and significant correlations with CC shape variation. Slower responses in attentional control were systematically associated with more curved and thinner CC, with consequent rotation of the splenium and the genu. Although the magnitude of the correlations suggests a small relationship of midsagittal CC geometry and attention, the results provide interesting clues regarding the links between brain anatomical configuration and human cognitive function.Brain Structure and Function 05/2012; · 7.84 Impact Factor
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ABSTRACT: To characterize the cavum septum pellucidum et vergae (CSPV) in normal fetuses in the second to third trimester. The cavum septum pellucidum (CSP) and CSPV were investigated in 322 uncomplicated singleton pregnancies from 25 to 39 weeks' gestation. Visualization rate, width, and morphology of both CSP and cavum vergae (CV) were assessed by ultrasound and MRI. The CSP and CSPV visualization rates were 100% and 7.8% (25/322), respectively. The mean widths were 6.3 ± 1.2 mm (3.4-10 mm) and 6.7 ± 1.0 mm (5.1-9 mm), respectively, with no significant correlation between width and gestational age (r = -0.108, p > 0.05 and r = -0.182, p > 0.05, respectively). In CSPV fetuses, the CV to CSP ratio was 1.004 ± 0.018 (0.967-1.033). All CSPVs were rectangular in the transverse plane and extended posteriorly beyond the midpoint of the brain. Common features of CSPVs include (1) a rectangular morphology, (2) communication between the two cavities, (3) a CV width within the normal range for CSP, and (4) a CV-CSP ratio of 1. These findings may help distinguish normal from abnormal CSPV. © 2013 Wiley Periodicals, Inc. J Clin Ultrasound, 2013.Journal of Clinical Ultrasound 08/2013; · 0.80 Impact Factor
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ABSTRACT: Colloid cysts are usually located at the rostral part of the third ventricle in proximity to the foramina of Monro. Some third ventricular colloid cysts, however, attain large sizes, reach a very high distance above the roof of the third ventricle, and pose some challenges during endoscopic excision. These features led to the speculation that for such a pattern of growth to take place, the points of origin of these cysts should be at areas away from the foramina of Monro at which some anatomical "windows" exist that are devoid of compact, closely apposed forniceal structures.Surgical Neurology International 01/2014; 5:124. · 1.18 Impact Factor