No link between low-grade periodontal disease and preterm birth: a pilot study in a healthy Caucasian population.
Faculty of Odontology, University of Iceland, Reykjavik.Acta Odontologica Scandinavica (impact factor: 1.07). 07/2004; 62(3):177-9. DOI:10.1080/00016350410001522 pp.177-9
Article: Association between periodontal status and pre-term and/or low-birth weight in Spain: clinical and microbiological parameters.[show abstract] [hide abstract]
ABSTRACT: BACKGROUND AND OBJECTIVE: Studies performed over the last 15 years have suggested that periodontal diseases may be associated with adverse pregnancy outcomes. However, this association has not been found in all populations. The aim of this study was to evaluate whether periodontal status and the presence of specific periodontal pathogens may influence the incidence of adverse pregnancy outcomes. MATERIAL AND METHODS: Pregnant women were clinically examined before 26th week of gestation, and divided in two groups: non-periodontitis and periodontitis. Microbial samples were obtained in the periodontitis group and processed by anaerobic culturing. After delivery, data on the pregnancy outcome were taken; mother's socio-demographic and risk factors were obtained at inclusion. Simple and multiple regression analysis were performed. RESULTS: One hundred and seventy women were included in the study (116 non-periodontitis and 54 with periodontitis). The incidence of preterm (PTB) and low-birth weight (LBW) was 2.94% and 3.53%, respectively. Periodontal status did not show any association with adverse pregnancy outcomes. The presence of Eikenella corrodens was significantly related to PTB (p = 0.022) and the presence Capnocytophaga spp. was related to LBW (p = 0.008). The multivariate analyses showed a significant association between PTB and newborn weight and counts of E. corrodens. Maternal health and counts of E. corrodens were significantly associated with PTB or LBW. CONCLUSION: The clinical periodontal condition was not associated with adverse pregnancy outcomes in a Spanish Caucasian population with medium-high educational level. The presence and counts of E. corrodens and the presence of Capnocytophaga spp. showed a significant association with PTB and LBW, respectively, in the bivariate and/or multivariate model.Journal of Periodontal Research 10/2012; · 1.69 Impact Factor
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ABSTRACT: Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Periodontal disease is a chronic inflammatory disease caused by infection in the supporting tissues of teeth and frequently results in tooth mobility and tooth loss. Approximately 10% of the adult population suffers from serious destruction of the tooth supporting tissues (periodontitis), but much higher percentage have inflammation in the gingival tissues without having lost support for the teeth. In resent years interest has emerged if there could be a link between periodontal disease and some common diseases like cardiovascular diseases and diabetes. Also, preterm birth has been discussed in this perspective. The surge of interest is, if there could be a causative link between infected oral cavity and these common diseases. The biologic rationale given, focuses on the role of general immune reaction and the role inflammatory mediators evoked by the oral infection. The purpose of this paper is to discuss current views on the connection of periodontal disease and some common general diseases. Tannholdsbólga er krónísk bólga sem stafar af sýkingu í stoðvefjum tannanna og leiðir oft af sér tannlos. Gera má ráð fyrir að um 10% fullorðinna hafi orðið fyrir alvarlegum skaða á stoðvefjum tannanna (periodontitis) vegna tannholdsbólgu, en mun fleiri hafa langvarandi þrota í tannholdinu (gingivitis) án þess að skemmd hafi orðið á festu tannanna. Á seinni árum hefur athyglin beinst að því hvort tengsl kunni að vera milli tannholdsbólgu og nokkurra algengra sjúkdóma, svo sem hjarta- og æðasjúkdóma og sykursýki. Einnig hefur athygli beinst að tengslum tannholdsbólgu við fæðingu fyrirbura. Það er ljóst að þessi fyrirbæri eiga sér sameiginlega áhættuþætti en rannsóknir beinast að því að kanna hvort um orsakasamhengi geti verið að ræða. Líffræðilegar orsakir eru taldar geta tengst staðbundinni og almennri ónæmissvörun við tannholdsbólgunni og áhrifum ónæmisboðefna á líkamann, ásamt því að sýkt munnhol getur verið orsök þess að bakteríur komast inn í blóðrásina. Þessi grein reifar þær kenningar sem uppi eru um tengsl tannholdsbólgu við nokkra almenna sjúkdóma með tilvísunum í rannsóknir sem fyrir liggja.
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