Article

Physical Activity/Exercise and Type 2 Diabetes

Department of Medicine, University of Ottawa, Canada.
Diabetes Care (Impact Factor: 8.57). 11/2004; 27(10):2518-39. DOI: 10.2337/diaspect.18.2.88
Source: PubMed

ABSTRACT F or decades, exercise has been consid-ered a cornerstone of diabetes man-agement, along with diet and medication. However, high-quality evi-dence on the importance of exercise and fitness in diabetes was lacking until recent years. The last American Diabetes Associ-ation (ADA) technical review of exercise and type 2 diabetes (formerly known as non–insulin dependent diabetes) was published in 1990. The present work emphasizes the advances that have oc-curred since the last technical review was published. Major developments since the 1990 technical review include: ● Advances in basic science, increasing our understanding of the effects of ex-ercise on glucoregulation. ● Large clinical trials demonstrating that lifestyle interventions (diet and exer-cise) reduce incidence of type 2 diabe-tes in people with impaired glucose tolerance (IGT). ● Meta-analyses of structured exercise in-terventions in type 2 diabetes showing: 1) effectiveness of exercise in reducing HbA 1c , independent of body weight; and 2) association between exercise training intensity and change in HbA 1c . ● Large cohort studies showing that low aerobic fitness and low physical activity level predict increased risk of overall and cardiovascular disease (CVD) mor-tality in people with diabetes. ● Clinical trials showing effectiveness of resistance training (such as weight lift-ing) for improving glycemic control in type 2 diabetes. ● New data on safety of resistance train-ing in populations at high risk for CVD.

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