Article

Alcohol and risk of atrial fibrillation or flutter: a cohort study.

Department of Cardiology, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark.
Archives of Internal Medicine (Impact Factor: 13.25). 11/2004; 164(18):1993-8. DOI: 10.1001/archinte.164.18.1993
Source: PubMed

ABSTRACT The evidence for an association between alcohol consumption and risk of atrial fibrillation is conflicting.
We prospectively examined the association between alcohol consumption and risk of atrial fibrillation or flutter among 47 949 participants (mean age, 56 years) in the Danish Diet, Cancer, and Health Study. The consumption of alcohol was analyzed as sex-specific quintiles by Cox proportional hazards regression models.
The mean +/- SD consumption of alcohol per day was 28.2 +/- 25 g in men and 13.9 +/- 15 g in women. During follow-up (mean, 5.7 years), atrial fibrillation or flutter developed in 556 subjects (374 men and 182 women). After adjusting for established risk factors, there was a modest increase in risk of atrial fibrillation or flutter by increasing alcohol consumption in men. When using the lowest quintile of alcohol consumption in men as a reference, the adjusted hazard rate ratios in men in quintiles 2, 3, 4, and 5 were 1.04, 1.44, 1.25, and 1.46, respectively (P for trend, .04). When using the lowest quintile of alcohol consumption in women as a reference, the adjusted hazard rate ratios in women in quintiles 2, 3, 4, and 5 were 1.09, 1.27, 1.23, and 1.14, respectively (P for trend, .69). Inclusion of information on the frequency of alcohol consumption and the preferred source of alcohol did not change these associations.
Consumption of alcohol was associated with an increased risk of atrial fibrillation or flutter in men. In women, moderate consumption of alcohol did not seem to be associated with risk of atrial fibrillation or flutter.

Download full-text

Full-text

Available from: Lars Frost, Jun 15, 2015
0 Followers
 · 
63 Views
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Alcoholism is a growing medical and public health issue both in adult and in younger populations. It is a multi-aetiological phenomenon influenced by genetic, psychological, cultural and other factors. Alcoholic beverages have traditionally been prepared from various ingredients, such as grapes, malt, and rice. Drinking prevalence has varied and is more pronounced in women and the youth. Alcoholism is shown to be of neurophysiologic origin and may lead to the impairment of all human body systems. The most frequent cause of death in alcoholics are the diseases of the cardiovascular system. Alcoholism at workplace is a very important issue as it affects health, reduces productivity, and may lead to accidents, injuries and decreased working capacity. Alcohol-related difficulties develop much earlier than the clinical picture. The diagnosis of alcoholism includes early detection of alcohol-related problems, so it is necessary to orient the healthcare services towards primary prevention and early intervention.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: El objetivo del presente estudio fue realizar una aproximación exploratoria para caracterizar el patrón de consumo recreativo abusivo de alcohol y otras drogas que se da en las cenas navideñas de empresa. Para ello se ha empleado una adaptación de la metodología de estimación rápida RARE, mediante la combinación de técnicas cuantitativas (encuestas de estimación rápida, n=444) y cualitativas (observaciones y entrevistas semiestructuradas, n=8). El trabajo de campo se desarrolló en 13 restaurantes de las ciudades de Valencia y Alicante (España) durante el mes de diciembre de 2007. En líneas generales se percibe un notable aumento del consumo de alcohol y otras sustancias en comparación al resto del año, si bien este año el consumo abusivo de alcohol, según los hosteleros, ha bajado respecto a años anteriores debido a la legislación vigente en materia de controles de tráfico. La cocaína es la sustancia ilegal percibida como más consumida en estos eventos. Los jóvenes inician en el consumo de sustancias ilegales a los adultos, quienes utilizan dicha conducta como vía de rejuvenecimiento y desinhibición. Las cenas navideñas de empresa propician un patrón de consumo recreativo que requiere de medidas preventivas y restrictivas adaptadas, tales como la puesta en marcha de medios de transporte adecuados para estos eventos y la restricción de horarios para el servicio de alcohol.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Atrial fibrillation (AF) is the most frequent maintained arrhythmia and constitutes a major morbidity cause, especially because of its associated risk of ischemic stoke. Additionally, it represents an independent risk factor for global mortality. The incidence of AF varies, according to different studies, between a minimum of 0.25 per 1000 person/year (women) and 0.9 per 1000 person/year (men) and a maximum of 8.9 per 1000 person/year (women) and 11.5 per 1000 person/year (men). Several cross sectional and prospective studies indicate that the prevalence of AF is inferior to 1% in individuals who are less than 55 years old. It is estimated that this arrhythmia's suffers a significant increase throughout the entire life span, and that its highest raise occurs between the ages of 65 and 80. A Portuguese study performe d between June and November 2003, in the scope of Rede Médicos-Sentinela, showed an AF prevalence of 0.53% in a population of 32,185 Health Centres patients. The mean age of patients suffering from this disease is situated within the interval of 70 to 80 years old. It is inferior for those who suffer from a concomitant cardiovascular disease, being significantly higher for women versus men. The risk factors and comorbidities which are most commonly associated to AF are age, several cardiovascular conditions, alcoholism, family history of AF and hyperthyroidism. Considering the high rate of stroke mortality in Portugal and assuming that AF is present in 15% ischemic stroke triggering and that it increases its risk 2 to 7 times, it can be concluded that knowledge regarding AF's incidence and prevalence in the different age groups will be important in order to improve its level of control, which is essential for preventing stroke and better management of this condition's treatment in the cardiovascular diseases' general context.
    Revista portuguesa de cardiologia: orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology: an official journal of the Portuguese Society of Cardiology 29(7-8):1207-17. · 0.53 Impact Factor