Article

Multiple sclerosis and celiac disease: is there an increased risk?

Clinica Pediatrica, Università dell'Insubria, Varese, Italy.
Multiple Sclerosis (impact factor: 4.26). 01/2005; 10(6):711-2. pp.711-2
Source: PubMed

ABSTRACT Multiple sclerosis and celiac disease are both considered immune-mediated diseases. Recently, improved serological screening methods provided a higher prevalence of celiac disease (CD) in the general population worldwide and also demonstrated gastrointestinal symptoms may be lacking. The aim of this study was to determine the prevalence of (CD) in an unselected group of 95 adults with multiple sclerosis using transglutaminase antibodies. No patients showed pathological values. Different immune and genetic basis between the two diseases may represent crucial insights to explain our results.

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Keywords

celiac disease
 
gastrointestinal symptoms
 
general population
 
genetic basis
 
higher prevalence
 
immune-mediated diseases
 
multiple sclerosis
 
pathological values
 
serological screening methods
 
unselected group