Acute plastic bronchitis.

Institute of Child Health, Chennai, India.
Indian pediatrics (Impact Factor: 1.04). 01/2005; 41(12):1257-9.
Source: PubMed


Plastic bronchitis is a rare disorder characterized by the formation of bronchial cast. The etiology is obscure, though usually associated with conditions like asthma, aspergillosis, pneumonia, cystic fibrosis and cardiac problems.

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    ABSTRACT: Cast bronchitis is a rare but potentially fatal condition caused by the accumulation of mucus in the bronchial tree usually secondary to infection, inflammation, or vascular stasis. Air leakage is an uncommon presentation of cast bronchitis. We report on three children with cast bronchitis who presented with acute air leakage as the main clinical feature. All three patients underwent bronchoscopic evaluation that led to a diagnosis and removal of bronchial casts. Pathologic examination of casts from all three patients showed a mucoid substance with eosinophilic infiltration. The outcome for all patients was favorable. Acute respiratory failure presenting with wheezing and thoracic air leakage refractory to standard asthma therapy should raise suspicion of cast bronchitis, and urgent bronchoscopy should be performed.
    Chest 09/2009; 136(2):615-7. DOI:10.1378/chest.08-0383 · 7.48 Impact Factor
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    ABSTRACT: A 17-months-old boy presented with left pulmonary atelectasis associated with plastic bronchitis which was diagnosed and removed by fibroscopy. No other specific pathogenetic factor was found, except for a nonexistent serum IgA level. A bocavirus was found in the patient's broncho-alveolar lavage fluid. In order to better characterize the profile of plastic bronchitis disease, we have reviewed the data in the pediatric literature, consisting of some small series and isolated case reports, published in the last 30 years. The level of detail was sufficient in 51 observations – including the case presented here – to allow us to make an analytical evaluation of the symptoms, the evolution, the predisposing factors and the histological type of this disease. Plastic bronchitis is a rare disease whose mechanisms remain hypothetical.
    Revue Française d Allergologie 03/2012; 52(2). DOI:10.1016/j.reval.2011.07.015 · 0.25 Impact Factor

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