Small lymphocytic lymphoma involving an enlarging complex renal cyst
Department of Pathology and Laboratory Medicine, Veterans Affairs Medical Center, Gainesville, FL 32608-1197, USA.Archives of pathology & laboratory medicine (Impact Factor: 2.84). 02/2005; 129(1):111-2. DOI: 10.1043/1543-2165(2005)129<111:SLLIAE>2.0.CO;2
A 47-year-old white man presented for evaluation of a complex right renal mass. He had a history of human immunodeficiency virus. Cervical lymph node biopsy had revealed small lymphocytic lymphoma. Computed tomographic scan disclosed diffuse mesenteric and retroperitoneal adenopathy consistent with chronic lymphocytic leukemia, as well as a 4.5-cm complex cystic right renal mass, which 17 months later enlarged to 6.2 cm. The mass resembled multiloculated cystic nephroma. Partial nephrectomy revealed infiltration of the cyst wall by small lymphocytic lymphoma. To our knowledge, this is the first reported case of lymphoma arising in or colonizing a renal cyst.
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ABSTRACT: Low-grade non-Hodgkin lymphomas frequently involve extranodal sites including the gastrointestinal tract, skin, and lung, either selectively or as part of widespread dissemination. Differentiation from inflammatory or infectious conditions requires knowledge of specific histologic characteristics of the various entities as well as ancillary techniques. To describe the key features and provide diagnostic clues to the identification of specific extranodal low-grade lymphomas of T-cell and B-cell types including small lymphocytic lymphoma, follicular lymphoma, mantle cell lymphoma, extranodal marginal zone B-cell lymphomas of mucosal-associated lymphoid tissue, and hairy cell leukemia. Histologic and cytologic features are highlighted, as well as appropriate integration of results of ancillary diagnostic studies including flow cytometry, immunohistochemistry, molecular features, and cytogenetics. The published literature as well as personal experience from a specialized hematopathology practice at a large university medical center. Correct identification of extranodal low-grade lymphomas and differentiation from hyperplastic and inflammatory or infectious processes require the ability to distinguish each of the specific entities discussed. Ancillary studies are often indispensable in reaching a correct diagnosis.Archives of pathology & laboratory medicine 04/2007; 131(3):383-96. DOI:10.1043/1543-2165(2007)131[383:SLPIEL]2.0.CO;2 · 2.84 Impact Factor
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ABSTRACT: Primary renal lymphomas are very rare, and primary kidney-limited lymphomas with cystic presentation have never been described before. This study reports a case of diffuse large B-cell lymphoma associated with chronic inflammation occurring in a renal pseudocyst: an infrequent neoplasm with an unusual and subtle clinical presentation.International Journal of Surgical Pathology 02/2011; 19(1):117-9. DOI:10.1177/1066896910391253 · 0.95 Impact Factor
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