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Stereospecific synthesis of new 4-amino-1,2,3-cyclohexanetricarboxylic acids and 4-amino-1,3-cyclohexanedicarboxylic acids.

Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, Japan.
CHEMICAL & PHARMACEUTICAL BULLETIN (Impact Factor: 1.56). 02/2005; 53(1):81-5. DOI: 10.1002/chin.200531081
Source: PubMed

ABSTRACT Diels-Alder adducts of 1,2-dihydropyridine with maleic and acrylic acid derivatives were stereospecifically converted by way of RuO4 oxidation into new 4-amino-1,2,3-cyclohexanetricarboxylic acids and 4-amino-1,3-cyclohexanedicarboxylic acids.

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