Article

Autoimmune pancreatitis: pathological findings.

Department of Pathology, University of Kiel, Kiel, Germany.
JOP: Journal of the pancreas 02/2005; 6(1 Suppl):97-101. pp.97-101
Source: PubMed

ABSTRACT In recent years, autoimmune pancreatitis has been established as a special type of chronic pancreatitis. It is characterized by its histopathological and immunological features. The morphological hallmarks are periductal infiltration by lymphocytes and plasma cells and granulocytic epithelial lesions with consequent destruction of the duct epithelium and venulitis. Autoimmune pancreatitis has therefore also been called lymphoplasmacytic sclerosing pancreatitis, duct-destructive chronic pancreatitis, or sclerosing pancreatitis. Autoimmune pancreatitis most commonly involves the head of the pancreas and the distal bile duct. Occasionally, masses are formed and it has been described as an inflammatory myofibroblastic tumor.

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    Nigel K F Koo Ng, Jin J Bong, Robin C Williamson
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    Sönke Detlefsen, J-Matthias Löhr, Asbjørn M Drewes, Jens B Frøkjær, Günter Klöppel
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Keywords

autoimmune pancreatitis
 
chronic pancreatitis
 
consequent destruction
 
distal bile duct
 
duct-destructive chronic pancreatitis
 
granulocytic epithelial lesions
 
immunological features
 
inflammatory myofibroblastic tumor
 
lymphocytes
 
lymphoplasmacytic sclerosing pancreatitis
 
plasma cells
 
recent years
 
sclerosing pancreatitis