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Systematic review of the effect of smoking on nonsurgical periodontal therapy.

Periodontology 2000 (Impact Factor: 3). 02/2005; 37:124-37. DOI: 10.1111/j.1600-0757.2004.03793.x
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    ABSTRACT: bersetzt aus: Chambrone L, Pannuti CM, Guglielmetti MR, Chambrone LA. Evidence grade associating periodontitis with preterm birth and/or low birth weight. II. A systematic review of randomized trials evaluating the effects of periodontal treatment. Zusammenfassung Ziel: Das Ziel dieses systematischen Reviews war, herauszufinden, ob eine par-odontale Behandlung während der Schwangerschaft (PATHM) das Risiko einer Frühgeburt (FG) und/oder eines niedrigen Geburtsgewichts (NGGW) reduzieren kann. Material und Methoden: Das Cochrane Zentral-Register für kontrollierte Studien sowie MEDLINE und EMBASE wurden auf eingereichte Artikel zu Untersuchun-gen in jeglicher Sprache durchsucht, die bis Oktober 2010 eingegangen waren. Ein-geschlossen wurden nur randomisierte, kontrollierte klinische Studien (RKSs), die den Effekt von PATHM auf den Geburstermin und das Geburtsgewicht untersucht haben. Die Literaturrecherche wurde von zwei unabhängigen Autoren durchgeführt. Random-Effekt-Metaanalysen wurden methodisch durchgeführt. Ergebnisse: Die Daten von dreizehn RKSs wurden untersucht, jedoch zeigten nur fünf Studien ein geringes Risiko für systematische Fehler. Die Ergebnisse von acht Untersuchungen (61,5 %) konnten zeigen, dass das Risiko für FG und/oder NGGW durch PATHM reduziert werden kann. Die Ergebnisse der Meta-Analysen zeigten jedoch gegensätzliche Ergebnisse für die Parameter FG [RR: 0,88 (95 % KI: 0,72; 1,09)], NGGW [RR: 0,78 (95 % KI: 0,53; 1,17)] und FG/NGGW [RR: 0,52 (95 % KI: 0,08; 3,31)]. Schlussfolgerungen: Die Ergebnisse dieses Reviews konnten zeigen, dass PATHM das Risiko für FG und/oder NGGW nicht reduzieren konnte; künftige Untersuchungen sollten allerdings den Einfluss spezifischer Parameter (Diagno-se, Ausmaß und Schwere sowie der Therapieerfolg) hinsichtlich der Ergebnisse berücksichtigen.
    Journal Of Clinical Periodontology 01/2011; 38:72-87. · 3.61 Impact Factor
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    ABSTRACT: This cross-sectional study addressed the relationship between coffee consumption and periodontitis in patients during the maintenance phase of periodontal treatment. A total of 414 periodontitis patients in the maintenance phase of periodontal treatment completed a questionnaire including items related to coffee intake and underwent periodontal examination. Logistic regression analysis showed that presence of moderate/severe periodontitis was correlated with presence of hypertension (Odds Ratio (OR) = 1.99, p < 0.05), smoking (former, OR = 5.63, p < 0.01; current, OR = 6.81, p = 0.076), number of teeth present (OR = 0.89, p < 0.001), plaque control record ≥20% (OR = 1.88, p < 0.05), and duration of maintenance phase (OR = 1.07, p < 0.01). On the other hand, presence of severe periodontitis was correlated with smoking (former, OR = 1.35, p = 0.501; current, OR = 3.98, p < 0.05), coffee consumption (≥1 cup/day, OR = 0.55, p < 0.05), number of teeth present (OR = 0.95, p < 0.05), and bleeding on probing ≥ 20% (OR = 3.67, p < 0.001). There appears to be an inverse association between coffee consumption (≥1 cup/day) and prevalence of severe periodontitis in the maintenance phase of periodontal treatment.
    Nutrients 10/2014; 6(10):4476-90. DOI:10.3390/nu6104476 · 3.15 Impact Factor
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    ABSTRACT: Despite the fact that several clinical studies have shown additional benefits when certain systemic antibiotics are used as adjuncts to periodontal treatment, clear guidelines for the use of these agents in the clinical practice are not yet available. Basic questions concerning the use of systemic antibiotics to treat periodontitis remain unanswered, such as: which drug(s) should be used; which patients would most benefit from treatment; which are the most effective protocols (i.e. doses and durations); and in which phase of the mechanical therapy should the drug(s) be administered? Although not all of those questions have been directly addressed by controlled randomized clinical trials, recent concepts related to the ecology of periodontal diseases, as well as the major advances in laboratory and clinical research methods that have occurred in the past decade, have significantly broadened our knowledge in this field. This article endeavored to provide a ‘state of the art’ overview on the use of systemic antibiotics in the treatment of periodontitis, based on the most recent literature on the topic as well as on a compilation of data from studies conducted at the Center of Clinical Trials at Guarulhos University (São Paulo, Brazil) from 2002 to 2012.
    Periodontology 2000 02/2015; 67(1). DOI:10.1111/prd.12075 · 3.00 Impact Factor

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