Article

Mild and efficient molybdenum-mediated Pauson-Khand-type reaction.

Departamento de Química Orgánica, Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain.
Organic Letters (Impact Factor: 6.14). 03/2005; 7(3):431-4. DOI: 10.1021/ol047678u
Source: PubMed

ABSTRACT [reaction: see text] The molybdenum-mediated Pauson-Khand reaction promoted by Mo(CO)3(DMF)3 takes place under very mild conditions in the absence of any promoter. High yields in Pauson-Khand adducts are obtained in the cyclization of a wide variety of functionalized 1,6- and 1,7-enynes. Enynes bearing electron withdrawing groups at the alkene terminus are particularly good substrates.

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