Obstetrical complications of morbid obesity

Service de Gynécologie-Obstétrique et Médecine de la Reproduction.
Journal de Gynécologie Obstétrique et Biologie de la Reproduction (Impact Factor: 0.56). 01/2005; 33(8):739-44. DOI: 10.1016/S0368-2315(04)96636-7
Source: PubMed


To determine whether morbidly obese women have an increased risk of pregnancy complications and adverse perinatal outcome.
In a retrospective study, 2472 women with morbid obesity, defined as a body mass index (BMI) more than 40 were compared with normal weight women (BMI 20-25). Fisher and Student tests were used for statistical analysis.
In the group of morbidly obese mothers (BMI greater than 40) as compared with the normal weight mothers, there was an increased risk of the following outcomes: gravidic hypertension (7.7 vs 0.5%; p<0.05). preeclampsia (11.5 vs 2%; p<0.05), gestational diabetes (15.4 vs 1.8%; p<0.05), cesarean delivery (50 vs 15.4%; p<0.05), and macrosomia (42.3 vs 10.3%; p<0.05). However, we noted a lower rate of prematurity in the obese group (0 vs 11%). Even when morbidly obese women with preexisting diabetes and chronic hypertension were excluded from the analysis, significant differences in the perinatal outcomes still persisted.
Morbid obesity appears to be an independent risk factor for perinatal and gestational complications.

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    • "Additionally , women in group 4 were treated as a separate group despite the low number (n = 25). Morbidly obese women generally have higher complication rates than do obese women with a BMI between 30 and 40 [5] [8] [9]; however, the small sample size of this group limited the ability to observe significant differences compared with the reference group (group 1). Further, the study population originated from one department, which could have hampered the generalizability of the results. "
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