Article

Crystalloid deposits in the kidney.

Renal Unit, Royal Adelaide Hospital, North Terrace, Adelaide 5000, South Australia, Australia.
Nephrology (impact factor: 1.31). 03/2005; 10(1):81-3. DOI:10.1111/j.1440-1797.2005.00290.x pp.81-3
Source: PubMed

ABSTRACT Light chain-producing lymphoproliferative disorders such as multiple myeloma are frequently complicated by renal impairment. Typically, the renal biopsy of a patient with renal failure caused by multiple myeloma shows cast nephropathy, but occasionally crystals may be seen. We describe the case of a patient with acute renal failure caused by multiple myeloma in which, on renal and bone marrow biopsy, there were widespread crystalloid deposits. Crystalloid nephropathy is a very rare condition associated with multiple myeloma and other light chain-secreting disorders. An underlying lymphoproliferative disorder should be considered in the differential diagnosis if crystalloid deposits are seen on a renal or other tissue biopsy.

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Keywords

acute renal failure
 
bone marrow biopsy
 
crystalloid deposits
 
Crystalloid nephropathy
 
crystals
 
differential diagnosis
 
light chain-secreting disorders
 
multiple myeloma
 
nephropathy
 
rare condition
 
renal
 
renal biopsy
 
renal failure
 
renal impairment