A Markov model of the cost-effectiveness of human-derived follicle-stimulating hormone (FSH) versus recombinant FSH using comparative clinical trial data

University of Illinois at Chicago, Chicago, Illinois, United States
Fertility and Sterility (Impact Factor: 4.59). 04/2005; 83(3):804-7. DOI: 10.1016/j.fertnstert.2004.08.024
Source: PubMed


This study compared the cost and effectiveness of highly purified, human-derived follicle-stimulating hormone (FSH) (Bravelle) to recombinant FSH (Follistim) using Markov modeling and Monte Carlo simulation. One IVF treatment cycle resulted in costs of 11,584 dollars +/- 211 dollars for human-derived FSH and 12,762 dollars +/- 170 dollars for recombinant FSH, while three treatment cycles, holding the transition probabilities of the first cycle constant for the next two cycles, resulted in costs of 22,712 dollars +/- 1,107 dollars for human-derived FSH and 24,935 dollars +/- 1,205 dollars for recombinant FSH.

Download full-text


Available from: Hind Tellawi Hatoum, Apr 30, 2015
Show more