MRI brain volumetry in Rasmussen encephalitis: the fate of affected and "unaffected" hemispheres.

Department of Neuropathology, University of Bonn, Bonn, Germany.
Neurology (Impact Factor: 8.3). 04/2005; 64(5):885-7. DOI: 10.1212/01.WNL.0000152895.23010.52
Source: PubMed

ABSTRACT Rasmussen encephalitis (RE) is regarded as a unihemispheric disease. Serial three-dimensional MRIs of 18 patients under immunotherapy were analyzed volumetrically and planimetrically. Median volume loss was significantly higher in the affected than in the unaffected hemispheres (29.9 cm3/y vs 6.8 cm3/y). Correlation of the planimetrically and volumetrically assessed hemispheric ratios (HRs) was significant. The results support the concept of RE as a basically unilateral disease. Planimetric HR assessment is valid and time efficient.

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