Article

The adolescent outcome of hyperactive girls: self-report of psychosocial status.

Department of Psychology, Institute of Psychiatry, London, UK.
Journal of Child Psychology and Psychiatry (impact factor: 4.28). 04/2005; 46(3):255-62. DOI:10.1111/j.1469-7610.2004.00350.x pp.255-62
Source: PubMed

ABSTRACT The aim of the study was to clarify the developmental risk associated with hyperactive behaviour in girls in a longitudinal epidemiological design.
This was investigated in a follow-up study of girls who were identified by parent and teacher ratings in a large community survey of 6- and 7-year-olds as showing pervasive hyperactivity or conduct problems or the comorbid mixture of both problems or neither problem. They were later investigated, at the age of 14 to 16 years, with a detailed self-report interview technique.
Hyperactivity was a risk factor for later development, even allowing for the coexistence of conduct problems. Hyperactivity predicted academic problems and interpersonal relationship problems. Relationships with parents, by contrast, were not portrayed to be as problematic as relationships with peers and the opposite sex. Their psychological, social and occupational functioning was objectively rated to be more deviant and their self-report showed them to be more ambivalent about their future. There was a trend for hyperactivity to be self-reported as a risk for the development of continuing symptomatology but neither hyperactivity nor conduct problems were self-reported to be a risk for antisocial behaviour, substance misuse or low self-esteem in adolescence. However, they were at risk for the development of state anxiety.
The results suggested girls' pattern of functioning may differ from that of boys because girls self-report a more pervasive range of social dysfunction than that previously reported in boys.

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    Article: Neuroanatomical abnormalities in adolescents with attention-deficit/hyperactivity disorder.
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    ABSTRACT: Several neuroanatomic abnormalities have been reported in patients with attention-deficit/hyperactivity disorder (ADHD). However, findings are not always consistent, perhaps because of heterogeneous subject samples. Studying youths with documented familial ADHD provides an opportunity to examine a more homogeneous population. Twenty-four youths with a confirmed history of familial ADHD and 10 control youths underwent high-resolution structural magnetic resonance imaging examinations. Archived magnetic resonance imaging scan data from 12 control youths were included in the analysis to increase statistical power. Individually drawn region-of-interest methods were used to examine the frontal lobe gyri and caudate. Cerebral total tissue was similar between groups. The volumes of the right caudate and right inferior frontal lobe were larger in the ADHD youths compared with the control youths. Data from a subgroup of the ADHD youths suggest that increasing left caudate volume is associated with decreasing functional activation of this region. Because previous studies have focused primarily on younger subjects or used an extended age range, the present results may reflect neurodevelopmental changes specific to late adolescence in familial ADHD.
    Journal of the American Academy of Child and Adolescent Psychiatry 10/2008; 47(11):1321-8. · 4.98 Impact Factor

Keywords

academic problems
 
antisocial behaviour
 
comorbid mixture
 
conduct problems
 
detailed self-report interview technique
 
developmental risk
 
follow-up study
 
girls self-report
 
girls' pattern
 
hyperactive behaviour
 
hyperactivity
 
interpersonal relationship problems
 
large community survey
 
longitudinal epidemiological design
 
pervasive hyperactivity
 
risk factor
 
social dysfunction
 
state anxiety
 
substance misuse
 
teacher ratings