High Homeopathic Potencies Are Different from Potentized Solvent when Investigated with the REDEM Technology
To determine in a series of randomized blinded experiments using the REDEM technology whether differences between high homeopathic potencies and similarly potentized solvent can be detected.
A REDEM device was employed as a black box. Samples were measured in a capacitor that was connected to 60 individual oscillator circuits at frequencies between 250 and 930 KHz; their oscillation damping was recorded. In two experiments (3 and 4 replications) stable differences between a potentized 'mother tincture' and potentized solvent were assessed. Statistical analysis was done using ANCOVA.
Significant differences (p < 0.01) between remedy and control were found, mostly at the same oscillator frequencies. Those differences found for only one remedy always were at frequencies adjacent to frequencies with differences for other remedies. VISUAL ANALYSIS: Where output curves were not near 0, remedy values were higher than controls. Curves within a replication ran parallel, their distances varied. Between replications, curve shapes and remedy- control differences were similar, however, control curves varied in height. Control and remedy curves between experiments varied in shape. Effects increased with time and sample conductivity. Ethanol 43% as solvent eliminated the observed effects, use of polyethylene containers considerably attenuated them.
A probably physical difference was seen between potentized homeopathic remedies and potentized solvent. The differences are associated with sample age, solvent, and container material. The REDEM technology requires further investigation to determine the nature of the underlying mechanisms of the observed differences.
Available from: Stefania Milazzo
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ABSTRACT: Many cancer patients use homeopathic approaches to increase their body's ability to fight cancer, improve their physical and emotional well-being, and alleviate their pain resulting from the disease or conventional treatments. Homeopathy is highly controversial as there is no plausible mode of action for these highly diluted remedies. The aim of this systematic review is to summarize and critically evaluate the efficacy of homeopathic remedies used as a sole or additional therapy in cancer care. We have searched the literature using the databases: Amed (from 1985); CINHAL (from 1982); EMBASE (from 1974); Medline (from 1951); and CAMbase (from 1998). Randomised and non-randomised controlled clinical trials including patients with cancer or past experience of cancer receiving single or combined homeopathic interventions were included. The methodological quality of the trials was assessed by Jadad score. Six studies met our inclusion criteria (five were randomised clinical trials and one was a non-randomised study); but the methodological quality was variable including some high standard studies. Our analysis of published literature on homeopathy found insufficient evidence to support clinical efficacy of homeopathic therapy in cancer care.
European Journal of Cancer 03/2006; 42(3):282-9. DOI:10.1016/j.ejca.2005.09.025 · 5.42 Impact Factor
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ABSTRACT: To investigate trace elements in liquid homeopathic preparations and the influence of container material, storage duration, and potentisation.
Using inductively coupled plasma-mass spectroscopy (ICP-MS), we investigated (a) aqua bidestillata (ABD) stored for 12 h in either brown glass or high density polyethylene (HDPE) bottles; (b) ABD stored for 2 h in HDPE, the same additionally filled in brown glass bottle, and ABD potentised in brown glass up to C30; (c) -- at 3 different sample ages and with statistical analysis -- ABD C30 (brown glass), AgNO3 C30 (brown glass), and controls (unsuccussed, brown glass and HDPE).
Contamination of the initial ABD increased and element concentrations changed far more when stored in brown glass bottles than in HDPE. Effects were strongest during initial storage time and during the first potentisation step from mother tincture to C1; subsequent potentising steps produced no relevant changes. Potencies of AgNO3 and potencies of water contained similar contamination.
Potentising accelerates material exchange between container and solvent, mostly during succussion. Research on potentised preparations should use potentised controls with equal preparation and storage time. If physical and biological effects of potencies exist, contaminants might be one factor for their generation.
Forschende Komplementärmedizin / Research in Complementary Medicine 03/2006; 13(1):15-21. DOI:10.1159/000090415
Available from: Stephan Baumgartner
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ABSTRACT: Systematic assessment of the in vitro research on high potency effects.
Publications of experiments were collected through databases, experts, previous reviews, citation tracking. Inclusion criteria: stepwise agitated dilutions <10(-23); cells or molecules from human or animal. Experiments were assessed with the modified SAPEH score.
From 75 publications, 67 experiments (1/3 of them replications) were evaluated. Nearly 3/4 of them found a high potency effect, and 2/3 of those 18 that scored 6 points or more and controlled contamination. Nearly 3/4 of all replications were positive. Design and experimental models of the reviewed experiments were inhomogenous, most were performed on basophiles.
Even experiments with a high methodological standard could demonstrate an effect of high potencies. No positive result was stable enough to be reproduced by all investigators. A general adoption of succussed controls, randomization and blinding would strengthen the evidence of future experiments.
Complementary Therapies in Medicine 07/2007; 15(2):128-38. DOI:10.1016/j.ctim.2007.01.011 · 1.55 Impact Factor
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