Comparing MSLT and ESS in the measurement of excessive daytime sleepiness in obstructive sleep apnoea syndrome

Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, 00, Hong Kong
Journal of Psychosomatic Research (Impact Factor: 2.84). 02/2005; 58(1):55-60. DOI: 10.1016/j.jpsychores.2004.05.004
Source: PubMed

ABSTRACT The objective of this study is to compare the use of Multiple Sleep Latency Test (MSLT) and Epworth Sleepiness Scale (ESS) in measuring excessive daytime sleepiness (EDS) in patients with different severity of obstructive sleep apnoea syndrome (OSAS).
Two hundred ninety-six consecutive OSAS patients, with their EDS measured by a Chinese version of ESS and a five-nap MSLT, and their severity of OSAS (determined by respiratory disturbance index) by a nocturnal polysomnogram, were classified into mild (RDI 5-15/h, n=59), moderate (RDI 15-30/h, n=71) and severe (RDI >30/h, n=166) groups, respectively. Their ESS, MSLT and other sleep parameters were compared.
The severe group had significantly shorter mean sleep latency (MSL=6.26+/-4.90 min) than the moderate (8.26+/-4.57 min) and mild groups had (8.07+/-4.37 min). There was no significant difference in their ESS scores.
MSLT is better than ESS in the measurement of EDS in relation to the severity of OSAS in clinical patients.

  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: OBJECTIVE: To assess in an objective way the degree of alertness in patients with fibromyalgia through the Maintenance Wakefulness Test ( MWT). METHOD: Fifteen patients with fibromyalgia and 15 age and sex- matched healthy controls were sequentially selected. The inclusion criteria for fibromyalgia were the presence of at least 11 of the 18 tender points and diffuse pain during three months prior to evaluation. All participants answered the Epworth Sleepiness Scale (ESS) and underwent four 20 minutes sessions of MWT scheduled at 2-hour intervals. Mean sleep latency higher than 20 minutes or lower than 10 minutes was considered normal or pathological, respectively. RESULTS: Although ESS scores did not differ between fibromyalgia patients and controls, the fibromyalgia group showed a significant decrease in the sleep latency by MWT ( 9.9 ± 4.6 and 14.9 ± 5.1, respectively, p = 0.01). Pathological results were obtained in 66.7% of the patients, in comparison to 26.7% of the controls ( p = 0.03). CONCLUSION: In this pilot study, patients with fibromyalgia showed decrease in the sleep latency by the Wakefulness Maintenance Test.
    Revista Brasileira de Reumatologia 02/2008; 48(1):12-16. · 0.99 Impact Factor
  • Source
    The Open Sleep Journal 05/2011; 4(1):14-19. DOI:10.2174/1874620901104010014
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The aim of the present study was to evaluate the reliability of a new sleep questionnaire (sHUNT-Q) used in the Nord Trøndelag Health Study 3 (HUNT 3) performed between 2006 and 2008. Six of nine items were modified from a Norwegian version of the Karolinska Sleep questionnaire (KSQ). Overall, 50,839 (54%) out of 94,194 invited participated in HUNT 3. In a randomly selected group of participants, 297 (53%) out of 563 invited persons attended an interview by neurologists. The reliability of the sleep related questions was evaluated with Cohen´s kappa by blindly comparing the an-swers in the questionnaire with those from the semi-structured interview. Summary measure scores were calculated by summing the responses of the six modified KSQ questions, the three insomnia-related questions, and the two questions re-lated to respiratory disturbance during sleep. Agreement was calculated for dichotomized sum-score indexes based on 75% and 50% percentile cut-offs. Kappa values for the individual questions ranged from 0.35 to 0.52 in 3 x 3 tables while kappa for summary indexes in 2x2 tables ranged from 0.47 to 0.62. The best agreement between the interview and the questionnaire was found for respiratory disturbance defined as a summary measure score 50 percentile (kappa value 0.62, 95% CI 0.51-0.74). Reliability did not depend on the time between the HUNT questionnaire and the interview. The KSQ-based summary measure scores from the new sHUNT-Q sleep screening questionnaire may become a useful tool in epidemiological studies for identifying individuals with a persistent sleep disturbance.