Prevalence of and risk factors for paratuberculosis in purebred beef cattle

Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843, USA.
Journal of the American Veterinary Medical Association (Impact Factor: 1.67). 04/2005; 226(5):773-8. DOI: 10.2460/javma.2005.226.773
Source: PubMed

ABSTRACT To estimate the prevalence of paratuberculosis in purebred beef cattle in Texas and identify risk factors for seropositivity.
Epidemiologic survey.
4,579 purebred cattle from 115 beef ranches in Texas.
Blood was collected, and serum was analyzed for antibodies with a commercial ELISA. Fecal samples were collected and frozen at -80 degrees C until results of the ELISA were obtained, and feces from seropositive cattle were submitted for mycobacterial culture. Herd owners completed a survey form on management factors.
Results of the ELISA were positive for 137 of the 4,579 (3.0%) cattle, and 50 of the 115 (43.8%) herds had at least 1 seropositive animal. Results of mycobacterial culture were positive for 10 of the 137 (7.3%) seropositive cattle, and 9 of the 50 (18%) seropositive herds had at least 1 animal for which results of mycobacterial culture were positive. Risk factors for seropositivity included water source, use of dairy-type nurse cows, previous clinical signs of paratuberculosis, species of cattle (Bos taurus vs Bos indicus), and location.
Results suggested that seroprevalence of paratuberculosis among purebred beef cattle in Texas may be greater than seroprevalence among beef cattle in the United States as a whole; however, this difference could be attributable to breed or regional differences in infection rates or interference by cross-reacting organisms. Veterinarians should be aware of risk factors for paratuberculosis as well as the possibility that unexpected serologic results may be found in some herds.

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    • "Thorne and Hardin (1997) tested 1,954 cattle from 19 dairy and 68 beef herds by ELISA and determined animal and herd-level prevalence of 8% and 5% and 74% and 40% for dairy and beef herds, respectively. Roussel et al. (2005) "
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    • "Its causing agent (MAP) has also been linked to Crohn's disease in humans; however, causation has not been established (Uzoigwe et al. 2007). Estimates of prevalence of MAP in cattle in several countries ranged from 1.6% to 18% (Lilenbaum et al. 2007), whereas prevalence of MAP in beef cattle in several states of the US fluctuated between 3% and 9% (Thorne and Hardin 1997; Roussel et al. 2005; Hill et al. 2003). "
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    • "For the following scenario that we considered to be the most probable (Boelaert et al., 2000; Corti and Stephan, 2002; Dargatz et al., 2001; Douart 2002; Hacker et al., 2004; Hill et al., 2003; Hirst et al., 2004; Jakobsen et al., 2000; Jubb and Galvin, 2004; Kasravi and Nowrouzian, 2004; Manning and Collins, 2001; Muskens et al., 2000; Nielsen et al., 2000; Roussel et al., 2005; Sorensen et al., 2003; Tavornpanich et al., 2004; Van Schaik et al., 2003; Vanleeuwen et al., 2001; Wells and Wagner, 2000; Wells et al., 2002), 15,000 iterations were carried out: interherd prevalence ¼ 25% (Boelaert et al., 2000; Corti and Stephan, 2002; Dargatz et al., 2001; Jakobsen et al., 2000; Manning and Collins, 2001; Muskens et al., 2000; Nielsen et al., 2000; Vanleeuwen et al., 2001; Wells and Wagner, 2000; Wells et al., 2002), intraherd prevalence ¼ 4% (Douart, 2002; Hacker et al., 2004; Hill et al., 2003; Hirst et al., 2004; Jubb and Galvin, 2004; Kasravi and Nowrouzian, 2004; Roussel et al., 2005; Sorensen et al., 2003; Tavornpanich et al., 2004; Van Schaik et al., 2003; Wells et al., 2002), mean MAP concentration in the milk coming from the teat ¼ 10 MAP cells=mL (Giese and Ahrens, 2000; Lynch et al., 2007; Rademaker et al., 2007; Stabel et al., 2001), no fecal contam- ination. "
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