The body mass index and level of resection: Predictive factors for compensatory sweating after sympathectomy

Dept. of Thoracic Surgery, Hospital das Clínicas Heart Institute-Incor University of São Paulo Medical School, São Paulo, Brazil.
Clinical Autonomic Research (Impact Factor: 1.49). 04/2005; 15(2):116-20. DOI: 10.1007/s10286-005-0259-6
Source: PubMed


Compensatory sweating (CS) is the most common adverse event and the main cause of dissatisfaction among patients undergoing a VATS sympathectomy for the treatment of primary hyperhidrosis. It has been described that obese individuals experience more sweating than thinner ones. The aim of this study is to identify the Body Mass Index (BMI) and the level of resection as predictive factors for CS and its relation to levels of patient satisfaction following the procedure.
From October 1998 to June 2003, 102 patients undergoing VATS sympathectomies (51 for palmar hyperhidrosis, PH, and 51 for axillary hyperhidrosis, AH) were prospectively surveyed. They were divided into three groups according to their BMI: Group I was composed of 19 patients with BMI<20 (9 patients with PH and 10 with AH); Group II was composed of 52 patients with 20 < or =BMI<25 (25 with PH and 27 with AH); and Group III was composed of 31 patients with BMI > or =25 (17 with PH and 14 with AH). Each procedure was simultaneously and bilaterally performed under general anesthesia using two 5.5 mm trocars and a 30 degrees optic system.
Patients treated for PH (resection of T2-T3) had more severe CS than those with AH (resection of T3-T4) (p=0.007) and the greater the BMI, the greater the severity of the CS (p<0.001). No statistically significant difference was found between the BMI bands in relation to the degree of satisfaction (p=0.644), nor when we compared the degree of satisfaction to the degree of CS (p=0.316).
The greater the BMI, the more severe the CS, but this did not correlate with the patients' level of satisfaction. Avoiding the resection of T2 sympathetic ganglia is also important in reducing the intensity of CS.

29 Reads
  • Source
    • "Generally, it is known that increased body mass index (BMI) is related to increased perspiration. Therefore, patients with compensatory hyperhidrosis should work towards reducing perspiration by maintaining their BMI in the normal range [11]. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Compensatory hyperhidrosis or reflex hyperhidrosis is the increase in sweating in the postoperative stage of thoracic sympathectomy or lumbar sympathectomy. It shares several features with anxiety disorders and has a negative impact on a patient's quality of life. Oralglycopyrrolate is one of the treatment options available. This study reviewed case notes in a series of 19 patients with compensatory hyperhidrosis. We made a comparison between the Milanez de Campos score of a pre-glycopyrrolate medication group and the Milanez de Campos score of a post-glycopyrrolate medication group. The Beck Depression Inventory (BDI) score, Beck Anxiety Inventory (BAI) score, and autonomic nervous system (ANS) scale score were also compared between the pre-medication and post-medication groups. In the post-glycopyrrolate medication group, there was decrease in the Milanez de Campos score, BAI score, and BDI score (P < 0.05). But no meaningful change was seen in the ANS score in the post-glycopyrrolate medication group (P > 0.05). Glycopyrrolate is an effective medication in the treatment of compensatory hyperhidrosis that, can alleviate anxiety and improve patients' quality of life.
    The Korean journal of pain 01/2013; 26(1):89-93. DOI:10.3344/kjp.2013.26.1.89
  • Source
    • "Chou et al. asserted that reflex response in the sweating center of the hypothalamus could cause the underlying mechanism of compensatory sweating [13]. According to previous studies, various factors, such as the location of hyperhidrosis, sympathicotomy level, and surgical procedures including clamp, cut and resect can induce compensatory sweating [14,15]. Also, the severity of compensatory sweating is influenced by patient condition, such as obesity, primary complaint severity and T2 sympathetic ganglion resection [15]. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Video-assisted thoracic sympathicotomy plays an important for the treatment of essential hyperhidrosis. Patients are usually satisfied with the surgical outcome at the early post-operative period, but suffer recurrence and compensatory sweating in the late post-operative period. There are many sympathicotomy methods to minimize recurrence and compensatory sweating. We compared the outcome of sympathicotomy methods above the third rib (R3) and the fourth rib (R4) with regards to symptoms, satisfaction, recurrence, and compensatory palmar and axillary hyperhydrosis. From January 1999 to April 2009, 39 cases of thoracoscopic sympathicotomy at the third rib (R3), and 94 cases of thoracoscopic sympathicotomy at the fourth rib (R4) for palmar and axillary hyperhidrosis were compared for early and late post-operative satisfaction, compensatory sweating and recurrence. There was no sex or age difference between groups. Early satisfaction was 94.9% and 98.9% in the R3 group and R4 group, respectively. There was no difference in early satisfaction (94.9% in R3 and 98.9% in R4), late satisfaction (84.6% in R3 and 89.4% in R4), or recurrence (17.9% in R3 and 17.0% in R4) between groups. There was significant difference in compensatory sweating (71.8% in R3 and 33% in R4, p=0.002). R4 sympathicotomy demonstrated superior efficacy in the treatment of compensatory sweating compared to R3 in palmar and/or axillary hyperhidrosis.
    Korean Journal of Thoracic and Cardiovascular Surgery 04/2011; 44(2):154-8. DOI:10.5090/kjtcs.2011.44.2.154
  • Source
    • "In the search for improved outcomes, researchers have looked for possible predictive factors that would indicate better surgical outcomes. Failure in the primary treatment,4 postoperative compensatory hyperhidrosis,5 the level of resection of the sympathetic chain,6 and extension of the resection7 may negatively influence the results of the surgery.8,9 "
    [Show abstract] [Hide abstract]
    ABSTRACT: Video-assisted thoracic sympathectomy (VATS) is currently the procedure of choice for the definitive treatment of primary hyperhidrosis because it is an effective, safe, and minimally invasive method. The aim of VATS treatment is to improve the quality of life through the reduction of excessive sudoresis. The purpose of this study was to assess the quality of life after VATS for treating palmar hyperhidrosis according to gender. A total of 1044 patients who submitted to the surgical treatment for palmar hyperhidrosis from June 2000 to February 2008 were retrospectively evaluated. The patients were divided into two groups according to gender [719 (68.8%) females and 325 (31.2%) males]. There are no statistically significant differences between genders with regard to the quality of life in palmar hyperhidrosis patients (p = 0.726). In the interview that was performed 30 days after surgery, the quality of life in the two groups had improved, with no statistical difference between the groups. Patients with palmar hyperhidrosis present with an improvement in the quality of life after VATS regardless of gender.
    Clinics (São Paulo, Brazil) 06/2010; 65(6):583-6. DOI:10.1590/S1807-59322010000600004 · 1.19 Impact Factor
Show more