High-resolution CT of the lung: patterns of disease and differential diagnoses.
ABSTRACT High-resolution CT (HRCT) of the lung is a powerful tool for the investigation of patients with acute or chronic respiratory symptoms or diffuse parenchymal lung disease. Detailed knowledge of normal pulmonary anatomy and an understanding of how normal anatomy is altered in disease states are required to appreciate fully HRCT findings in patients with pulmonary disease. Detailed knowledge of the technical aspects of HRCT examinations is required for optimal image quality. With the proper foundation, a pattern approach to HRCT interpretation may then be used successfully to provide accurate and reproducible interpretation.
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ABSTRACT: To implement and assess the performance of three-dimensional (3D) ultra-short echo (UTE) time for evaluating lung tissue density changes induced by gravity dependence and lung inflation. Twelve healthy volunteers were imaged by 3D UTE at 3 Tesla, during free-breathing and breathholding of the subjects. MR signal intensities were measured in lung tissue and muscle regions. The variations of MR lung signal intensity and lung water content were evaluated as a function of lung inflation and anterior/posterior position. SNR in lung tissue ranged between 35 for free-breathing acquisitions and 7 for breathhold acquisitions at functional residual capacity. Lung-to-muscle signal ratios decreased from 0.58 in posterior areas to 0.34 in anterior areas. The average water content measured in lungs was equal to 34% and 58% in gravitationally nondependent and dependent regions of interest. The 3D UTE lung MRI provides signal within lung parenchyma and can be used to assess lung tissue density. J. Magn. Reson. Imaging 2013. © 2013 Wiley Periodicals, Inc.Journal of Magnetic Resonance Imaging 10/2014; 40(4). DOI:10.1002/jmri.24429 · 2.79 Impact Factor
Article: Headcheese SignJournal of thoracic imaging 01/2014; 29(1):W13. DOI:10.1097/RTI.0000000000000067 · 1.49 Impact Factor