To examine the influence of initial infant feeding on obesity in later life.
A systematic review of published studies investigating the association between infant feeding and a measure of obesity was performed with Medline (1966 onward) and Embase (1980 onward) databases, supplemented with manual searches. Data extraction was conducted by 2 authors. Analyses were based on odds ratios of obesity among initially breastfed subjects, compared with formula-fed subjects, pooled with fixed-effects models.
Sixty-one studies reported on the relationship of infant feeding to a measure of obesity in later life; of these, 28 (298900 subjects) provided odds ratio estimates. In these studies, breastfeeding was associated with a reduced risk of obesity, compared with formula feeding (odds ratio: 0.87; 95% confidence interval [CI]: 0.85-0.89). The inverse association between breastfeeding and obesity was particularly strong in 11 small studies of <500 subjects (odds ratio: 0.43; 95% CI: 0.33-0.55) but was still apparent in larger studies of > or =500 subjects (odds ratio: 0.88; 95% CI: 0.85-0.90). In 6 studies that adjusted for all 3 major potential confounding factors (parental obesity, maternal smoking, and social class), the inverse association was reduced markedly (from an odds ratio of 0.86 to 0.93) but not abolished. A sensitivity analysis examining the potential impact of the results of 33 published studies (12505 subjects) that did not provide odds ratios (mostly reporting no relationship between breastfeeding and obesity) showed little effect on the results.
Initial breastfeeding protects against obesity in later life. However, a further review including large unpublished studies exploring the effect of confounding factors in more detail is needed.
"The association between breastfeeding and childhood obesity is uncertain, and results are inconsistent: some studies show a strong association between breastfeeding and childhood obesity    while others do not [16– 18]. There are clinical studies that show that breastfeeding decreases the risk for adulthood obesity    . "
[Show abstract][Hide abstract] ABSTRACT: Objective:
The objective of this study was to evaluate whether duration of breastfeeding is associated with a lower prevalence of metabolic syndrome in obese children.
A retrospective analysis of obese children aged 3 to 18 years followed at a pediatric outpatient clinic at a single center between the years 2008 and 2012. The children were divided according to their breastfeeding duration: no breastfeeding, a short period of breastfeeding, and a long term breastfeeding. Also, they were divided into metabolic and nonmetabolic syndrome groups, based on physical examination and laboratory tests.
Out of 4642 children who visited the clinic, 123 were obese and were included in the study. About half of them matched the metabolic syndrome criteria. There was no correlation between the prevalence of metabolic syndrome and the duration of breastfeeding. Hypertension, abnormal low levels of HDL, high levels of HbA1c, and high fasting triglyceride levels were very common in our study population, yet no statistical significance was noted among the different breastfeeding groups.
In this study, breastfeeding was not associated with a reduced risk for metabolic syndrome, compared with formula feeding, in children who are obese.
The Scientific World Journal 08/2015; 2015(5):731319. DOI:10.1155/2015/731319 · 1.73 Impact Factor
"2. After birth – infant feeding. Breastfeeding, relative to formula feeding, is associated with a decreased risk of later obesity (Arenz et al., 2004; Owen et al., 2005), and women in lower SES groups are less likely to breastfeed (McAndrew et al., 2012). Furthermore, maternal depression, which is more prevalent in low-income households, can have a negative impact on the ability of mothers to breastfeed successfully (Gutman et al., 2009; Jennings et al., 1991). "
[Show abstract][Hide abstract] ABSTRACT: purpose - This paper was written as part of a suite to inform the Big Lottery Better Start programme and as such has focused on the outcomes that are of interest to that programme. The authors have also focused on outcomes for younger children and the zero to three years age group where data are available. There is a social gradient such that the lower a family's socio-economic status (SES) the greater the likelihood that they have children who are obese, have impaired social and emotional skills, or have impaired language acquisition. These statistics are clear and undisputed. The purpose of this paper is to explore some of the reasons for the social gradient in these outcomes. The paper provides some suggestions for actions that might be taken to redress the inequalities. It follows broader work presented in, for example, the Marmot (2010) review, Fair Society Healthy Lives.
Journal of Children's Services 06/2014; 9(2):83-95. DOI:10.1108/JCS-01-2014-0004
"This implies a greater discharge of growth hormone, insulin-like growth factor 1 and insulin into the bloodstream, resulting in adipocytes and of stocks of fat in artificially fed infants compared with naturally nourished individuals [33, 37]. Furthermore, it is suggested that as well as substitute feeding mixtures, a significant risk factor for obesity in children is posed by excessive maternal nutritional status during pregnancy, which has an impact on the development of the foetus [36, 37]. "
[Show abstract][Hide abstract] ABSTRACT: Breastfeeding is the most appropriate way to nourish infants. It promotes proper physical and intellectual development of the child. Human milk is unique and impossible to replicate with any other kind of food. However, using maternal milk not only has beneficial effects on the infant's health but it can also help to prevent illnesses in adulthood. Breastfeeding improves immunity and consequently decreases the occurrence of infections, especially those of the gastrointestinal tract and respiratory tract. More-over, it helps to reduce the risk of some disorders such as allergies, diabetes mellitus type 1, obesity and arterial hypertension.
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