Article

Liquorice and hypertension

The Netherlands Journal of Medicine (Impact Factor: 2.21). 05/2005; 63(4):119-20.
Source: PubMed

ABSTRACT Glycyrrhetinic acid, the active constituent of liquorice, inhibits renal IIbeta-hydroxysteroid dehydrogenase. This allows cortisol to stimulate mineralocorticoid receptors, which can result in hypertension and hypokalaemia. Treatment options are based on pathophysiological understanding.

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