Article

Population study of 11 Y-chromosomal STR loci in Singapore Chinese.

DNA Profiling Laboratory, Centre for Forensic Science, Health Sciences Authority, 11 Outram Road, 169078 Singapore, Singapore.
Forensic Science International (impact factor: 2.3). 05/2006; 158(1):65-71. DOI:10.1016/j.forsciint.2005.04.009 pp.65-71
Source: PubMed

ABSTRACT In this study of 212 unrelated Singapore Chinese males, allelic frequencies and gene diversities of 11 Y-chromosome specific STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS438 and DYS439) were established. A total of 184 haplotypes were observed in the 212 individuals studied, of which 165 (89.67%) were unique. The most common haplotype was observed in five (2.35%) individuals. The overall haplotype diversity for the 11 Y-STR loci was 99.81%, and the discrimination capacity was 86.79%.

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    Article: Haplotype diversity of 22 Y-chromosomal STRs in a southeast China population sample (Chaoshan area).
    Meisen Shi, Rufeng Bai, Xiaojun Yu, Junyao Lv, Bo Hu
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    ABSTRACT: In this study, 22 Y-specific STR loci (DYS19, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS385, DYS437, DYS438, DYS439, DYS461, DYS481, DYS504, DYS505, DYS508, DYS533, DYS576, DYS588, DYS607, DYS634, and DYS643) were analyzed in 216 unrelated male individuals from southeast China (Chaoshan area) by three multiplex PCR systems. The haplotype diversity using the classical set of Y-STRs (DYS19, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, and DYS385; PowerPlexY Systems) was 0.9908. For the same population sample, the haplotype diversity using the new sets of 11 novel Y-STRs (DYS461, DYS481, DYS504, DYS505, DYS508, DYS533, DYS576, DYS588, DYS607, DYS634, and DYS643; multiplex I and II) was 0.9917. By combining the allelic states of the 22 Y-STR loci we could construct highly informative haplotypes that allowed the discrimination of 99.1% (214 out of 216) of the samples tested and the overall haplotype diversity of 0.9999. These results, including the haplotype data at 22 Y-STR loci in the present study, provide useful information for forensic practice in the Chaoshan population in southeast China.
    Forensic science international. Genetics 04/2009; 3(2):e45-7. · 2.42 Impact Factor
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Keywords

11 Y-chromosome specific STR loci
 
184 haplotypes
 
212 unrelated Singapore Chinese males
 
allelic frequencies
 
common haplotype
 
discrimination capacity
 
haplotype diversity
 

June Sheau Wei Tang