P3-154 The relationships between television viewing in midlife and the development of Alzheimer disease in a case-control study

Department of Nutrition, Case Western Reserve University, Cleveland, Ohio, United States
Brain and Cognition (Impact Factor: 2.48). 08/2005; 58(2):157-65. DOI: 10.1016/j.bandc.2004.09.020
Source: PubMed


The relationship between leisure activities and development of cognitive impairment in aging has been the subject of recent research. We examined television viewing in association with risk of developing Alzheimer's disease (AD) in a case-control study. Given recent focus on the importance of intellectually stimulating activities as preventive measures against cognitive decline, it is important to examine the effects of less stimulating but common activities. Data are from 135 Alzheimer's disease cases and 331 healthy controls. Demographic characteristics and life history questionnaire responses on the number of hours spent on 26 leisure activities during middle-adulthood (ages 40-59) were analyzed. Logistic regression was used to examine the effects of middle-adulthood leisure activities on case vs. control status. Results indicate that for each additional daily hour of middle-adulthood television viewing the associated risk of AD development, controlling for year of birth, gender, income, and education, increased 1.3 times. Participation in intellectually stimulating activities and social activities reduced the associated risk of developing AD. Findings are consistent with the view that participation in non-intellectually stimulating activities is associated with increased risk of developing AD, and suggest television viewing may be a marker of reduced participation in intellectually stimulating activities.

26 Reads
  • Source
    • "related decline in cognitive function (Brown et al., 2012) yet less time watching TV in midlife may reduce risk of Alzheimer's disease later in life (Lindstrom et al., 2005). Physical exercise improves processing speed, spatial processing, and executive control (i.e., the selection, planning, and coordination of complex cognitive events) for older adults (Hertzog et al., 2008); however, little is known about the impact of physical activity and episodic memory in older adults, although the typical age-related atrophy in brain regions that mediate episodic memory (i.e., the hippocampus ) is reduced, and in some cases reversed, following an aerobic exercise intervention (Erickson et al., 2009). "
    [Show abstract] [Hide abstract]
    ABSTRACT: Objective: Physical and sociocognitive lifestyle activities promote aspects of cognitive function in older adults. Very little is known about the relation between these lifestyle activities and cognitive function in young adults. One aspect of cognitive function that is critical for everyday function is episodic memory. The present study examined the relationship between lifestyle activities and episodic memory in younger and older adults. Method: Participants were 62 younger (mean age = 24 years) and older adults (mean age = 74 years). The augmented Victoria Longitudinal Study Activities Questionnaire was used to quantify level of engagement in physical activity, sociocognitive activity, and TV viewing. Episodic memory was assessed using the old-new face recognition paradigm in which memory for younger and older faces was tested. Results: Compared to younger adults, older adults reported being less physically and sociocognitively active while engaging in more passive behaviors such as TV viewing. A positive association was observed between physical activity and episodic memory for young adults but not for older adults. Interestingly, TV viewing was negatively associated with episodic memory in older adults but not younger adults. No relationship was found between sociocognitive activity and episodic memory for either younger or older adults. Although the own-age effect was observed for older adults, face age did not interact with lifestyle activities. Conclusion: The positive cognitive benefits of physical activity extend to younger adults; however, the interplay between physical activity and cognition may differ across the life span. Furthermore, TV viewing may be particularly detrimental to cognitive performance later in life.
    Health Psychology 01/2014; 34(1). DOI:10.1037/hea0000046 · 3.59 Impact Factor
  • Source
    • "Similarly, long periods of television viewing may lead to impingement of neuronal mechanism leading to short attention span and a possibility of developing autism [52]. Furthermore, contemporary facts put forward suggest that television spectacle may have association with the development of Alzheimer's disease [53]. Television viewing has also been implicated in suppressing production of melatonin, a key hormone that has important roles in the immune system, sleep/wake cycle and the onset of puberty [54]. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Although cricket has origins in the British Empire, it is followed as a religion in South Asia, probably due to the influence of the former during their rule. The sport is equally popular among all groups of the society, and is not subject to gender or age constraints. It marks the epitome of reverence and is considered a battle for self-esteem, not only for those playing, but for those watching as well. The intensity of emotional attachment with this sport renders certain public health benefits as well as drawbacks to the general masses.
    International Archives of Medicine 07/2013; 6(1):30. DOI:10.1186/1755-7682-6-30 · 1.08 Impact Factor
  • Source
    • "There is increasing evidence that these activities may not activate neuronal circuits in ways that induce adaptive stress response pathways. For example, one study revealed a positive correlation between hours of television watching in midlife and the risk of developing Alzheimer's disease in old age (Lindstrom et al., 2005). A study of twins in Sweden demonstrated that the risk of Alzheimer's disease was greater in the twin with a lower level of education (Gatz et al., 2001). "
    [Show abstract] [Hide abstract]
    ABSTRACT: The impact of hormesis on health can be further appreciated by consideration of the couch potato lifestyle. When cells in the body and brain are not challenged, they become complacent and are therefore vulnerable to injury and disease. Lack of physical and mental exercise, in combination with excessive food intake, results in a condition called insulin resistance that is a harbinger of diabetes and cardiovascular disease. On the other hand, when fewer calories are consumed and when more energy is expended (exercise), cells are subjected to a mild metabolic stress. They respond to this mild stress adaptively by increasing their ability to take up glucose in respond to insulin. This hormesis response is, in part, responsible for the ability of dietary energy restriction and exercise to ward off diabetes and cardiovascular disease. However, obesity and diabetes are not the only adverse physiological consequences of being a couch potato. Exercise and dietary energy restriction improve the functional efficiency of the heart and gut through a hormetic mechanism that involves increased activity of the parasympathetic component of the autonomic nervous system. As a consequence, heart rate and blood pressure are decreased and gut motility is increased, thereby reducing the risk of heart disease, stroke, and colon cancer. Relatively underappreciated is the contribution of the lack of mental challenges to the poor health associated with the couch potato lifestyle. Individuals who engage in intellectually challenging occupations or hobbies may be at reduced risk for Alzheimer's disease because of the beneficial stress imposed on the neurons when they are challenged. Studies have shown that neurons respond to mental and physical activity by increasing their production of neurotrophic factors that may help them to resist disorders such as Alzheimer's disease and Parkinson's disease. © Springer Science+Business Media, LLC 2010 All rights reserved.
    Hormesis, 11/2009: pages 139-151;
Show more