Antiviral T cell responses: Phalanx or multipronged attack?

Department of Medicine, Division of Hematology-Oncology, Weill Medical College, Cornell University, New York, NY 10021, USA.
Journal of Experimental Medicine (Impact Factor: 12.52). 07/2005; 201(12):1881-4. DOI: 10.1084/jem.20050928
Source: PubMed


Around 700 BCE, a new military formation called the phalanx was established in ancient Greece: a tight column of heavy infantry carrying long spears, or pikes, used in a single prong of attack. Later, in the battle of Marathon described by Herodotus, the Greeks learned the advantages of multipronged attacks, a strategy still used in modern warfare. Is the immune system similar in its approach to combatting pathogens or tumors?

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