Article

Results of nonablative wrinkle reduction with a 1,450-nm diode laser: difficulties in the assessment of "subtle changes".

Department of Dermatology, University of Regensburg, 93042 Regensburg, Germany.
Lasers in Surgery and Medicine (impact factor: 2.75). 08/2005; 37(1):14-8. DOI:10.1002/lsm.20181 pp.14-8
Source: PubMed

ABSTRACT Nonablative resurfacing has proven its efficacy in vascular and pigmented lesions, while its capacity of substantial wrinkle reduction is still discussed controversially. We present the treatment results of a 1,450 nm diode laser for facial rhytides.
Thirty facial regions were treated with a 1,450 nm diode laser. Pre- and post treatment pictures were compared by the treating physician and two blinded observers.
Even if mild improvement was rated in up to 35% of the post treatment pictures, a discrepancy shows up in the assessments of the three observers, presenting almost no congruency in the rating of improvement.
Our study failed to provide convincing data on the efficacy of nonablative treatment of rhytides with the 1,450 nm diode laser. In this respect, we challenge objective judgment in the assessment of subtle changes in nonablative wrinkle reduction.

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Keywords

controversially
 
convincing data
 
discrepancy
 
efficacy
 
mild improvement
 
Nonablative resurfacing
 
nonablative treatment
 
nonablative wrinkle reduction
 
observers
 
post treatment pictures
 
Pre-
 
three observers
 
treating physician
 
treatment results