Fire during thoracotomy: A need to control the inspired oxygen concentration

Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, California, United States
Anesthesia & Analgesia (Impact Factor: 3.47). 09/2005; 101(2):612. DOI: 10.1213/01.ANE.0000159015.66892.D2
Source: PubMed
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    • "FIO 2 of 0.5 was evaluated because it is commonly used in anesthesia practice when higher supplemental oxygen is desired. Use of FIO 2 higher than 0.5 is not without risks [13] [14] [15] [16] [17]. "
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    ABSTRACT: To assess the efficacy of intraoperative inspired oxygen fractions (FIO(2)) of 0.8 and 0.5 when compared with standard FIO(2) of 0.3 in the prevention of postoperative nausea and vomiting (PONV). Prospective, randomized, double-blinded, controlled study. General hospital, postanesthesia care unit (PACU), and gynecology floor room. 120 ASA physical status I and II women, aged 21 to 76 years, undergoing elective gynecologic laparoscopic surgery. Patients were randomized to receive a gas mixture of 30% oxygen in air (FIO(2) = 0.3, Group G30), 50% oxygen in air (FIO(2) = 0.5, Group G50), or 80% oxygen in air (FIO(2) = 0.8, Group G80); there were 36 patients in each group. A standardized sevoflurane general anesthesia, postoperative pain management, and antiemetic regimen were used. Frequency of nausea, vomiting, and both was assessed for early (0 to two hrs) and late PONV (two to 24 hrs), along with use of rescue antiemetic, degree of nausea, and severity of pain. There was no overall difference in the frequency of PONV at the early and late assessment periods among the three groups. G80 patients had significantly less vomiting than Group G30 at two hours, 3% (1/36) vs. 22% (8/36), respectively, P = 0.028. Nausea scores, rescue antiemetic use, pain scores, and opioid consumption did not differ among the groups. High intraoperative FIO(2) of 0.8 and FIO(2) of 0.5 do not prevent PONV in patients without antiemetic prophylaxis. An intraoperative FIO(2) of 0.8 has a beneficial effect on early vomiting only.
    Journal of clinical anesthesia 11/2010; 22(7):492-8. DOI:10.1016/j.jclinane.2009.10.013 · 1.19 Impact Factor
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    TENCON '93. Proceedings. Computer, Communication, Control and Power Engineering.1993 IEEE Region 10 Conference on; 11/1993
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    ABSTRACT: Radiofrequency ablation (RFA) is an emerging therapy that is increasingly being used for the treatment of many different types of tumors. RFA uses percutaneously placed image-guided probes to destroy tissues through localized heating. Injury to adjacent tissues with significant morbidity during RFA has been reported in the literature. We discuss our anesthetic management of patients undergoing RFA of lung tumors. Lung isolation, one-lung ventilation, and nondependent lung continuous positive airway pressure with air can be used to minimize damage to the heart and other important structures.
    Anesthesia and analgesia 09/2006; 103(2):463-4, table of contents. DOI:10.1213/01.ane.0000223672.30521.d8 · 3.47 Impact Factor
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