Benign mullerian papilloma of childhood

Department of Pathology, The Children's Hospital, Denver, Colorado 80218, USA.
Ultrastructural Pathology (Impact Factor: 1.13). 05/2005; 29(3-4):209-16. DOI: 10.1080/01913120590951211
Source: PubMed

ABSTRACT Benign müllerian papilloma of the female reproductive tract is a rare childhood tumor that can easily be mistaken by those unfamiliar with the entity for botryoid rhabdomyosarcoma. Ultrastructural findings have been mentioned only in two individual case reports, and these both were issued many years ago. The aim of this update is to familiarize the reader with the clinical, light, and electron microscopic features associated with this distinctive entity, and thereby hopefully preclude the risk of making a serious diagnostic error. Two cases are illustrated, one very typical in its presentation and the other less so.

  • [Show abstract] [Hide abstract]
    ABSTRACT: Vaginal bleeding in premenarchal girls is always abnormal and its source must be identified for appropriate management. Examination under anesthesia and vaginoscopy are commonly employed for evaluation of the vagina as a source of bleeding, and the examination may occasionally reveal vaginal pathology. A 16-month-old otherwise healthy girl presented with spotting. Exam under general anesthesia and vaginoscopy revealed a 1-cm polypoid-like lesion overlying the posterior vaginal wall which was excised using the hysteroscope. Pathology revealed a benign Müllerian cyst. Vaginal findings of causes of premenarchal bleeding such as Mullerian cysts may be diagnosed and treated with the vaginoscopic approach.
    Journal of pediatric and adolescent gynecology 08/2013; DOI:10.1016/j.jpag.2013.06.004 · 0.90 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Vaginal bleeding in young girls is a distressing symptom. Due to the potential for malignancy, thorough investigation is needed. Though rare, Müllerian papillomas are a benign cause of such symptoms. We report the case of a 2-year-old female who presented with acute onset of vaginal bleeding. She had another episode of bleeding during admission and was taken to the operating room for vaginoscopy under general anesthesia. A single friable lesion with active bleeding was visualized near the anterior vagina or cervix, which was biopsied. Histopathologic examination demonstrated characteristic features of benign Müllerian papilloma of infancy. Müllerian papillomas require examination under anesthesia and vaginoscopy with biopsies for efficient and accurate diagnosis. Treatment consists of complete local excision. Local recurrences are not uncommon, though prognosis for primary or recurrent disease is excellent.
    Pediatric Surgery International 10/2014; DOI:10.1007/s00383-014-3630-7 · 1.06 Impact Factor
  • Journal of Minimally Invasive Gynecology 09/2012; 19(5):541-2. DOI:10.1016/j.jmig.2011.11.004 · 1.58 Impact Factor