Article

Assessing Quality of Life in Adult Cancer Survivors (QLACS)

Wake Forest University School of Medicine, Department of Public Health Sciences, Winston-Salem, NC 27157-1063, USA.
Quality of Life Research (Impact Factor: 2.86). 05/2005; 14(4):1007-23. DOI: 10.1007/s11136-004-2147-2
Source: PubMed

ABSTRACT This article describes development of a quality of life measure designed to assess issues relevant to long-term cancer survivors. In-depth semi-structured interviews were conducted with 58 long-term cancer survivors to identify domains most relevant to long-term survivors (> or = 5 years post-diagnosis). Self-report items were developed from these interviews and administered to a second sample of 242 long-term survivors. Domains and items were selected from the item pool by a combination of factor analysis and criterion-based item selection. Five cancer-specific domains were identified (appearance concerns, financial problems, distress over recurrence, family-related distress, and benefits of cancer) along with seven generic QOL domains (negative feelings, positive feelings, cognitive problems, sexual problems, physical pain, fatigue, and social avoidance). Cronbach's alpha was 0.72 or greater for each domain. Correlations between domain scores and criterion measures were 0.72 or higher in all but one generic domain (social avoidance), but somewhat lower on cancer-specific domains. The new multidimensional measure has good internal consistency and validity and is appropriate for comparisons between cancer and non-cancer populations, as well as long-term follow-up of cancer patients.

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    • "Many cancer-specific QOL measures have been developed, such as the Functional Adjustment to Cancer Therapy (FACT), European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (EORTC QLQ-C33), Functional Living Index-Cancer (FLIC), and Cancer Rehabilitation Evaluation System (CaRES/CaRES-SF).[1415] "
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    Indian Journal of Palliative Care 05/2014; 20(2):116-22. DOI:10.4103/0973-1075.132627
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    • "The survey queried post-cancer onset physical, emotional, and practical concerns as well as receipt of care for concerns. The concerns cited in the survey were initially included because: 1) they had been used in other surveys (e.g., the Quality of Life in Adult Cancer Survivors Scale (QLACS; (Avis et al., 2005); the National Cancer Institute's Health Information National Trends Survey (Hesse, Moser, Rutten, & Kreps, 2006)); 2) they were identified by the expert advisors as known late effects; and/or 3) they were addressed by LIVESTRONG educational resources. The survey was repeated in 2010 and collected data from a new sample of respondents. "
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    • "• The Quality of Life in Adult Cancer Survivors scale (QLACS) [29] assesses quality of life in five areas suggested by long-term survivors themselves as relevant to their lives (financial problems, benefits of cancer, appearance, distress related to recurrence and distress related to the family), and seven additional areas that are relevant but not limited to cancer (negative feelings; positive feelings; cognitive problems; pain; sexual interest; sexual function; energy/fatigue and social avoidance). QLACS has been validated amongst cancer survivors [29] and has good convergent validity with other QoL measures (e.g. "
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