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Renalase, a catecholamine-metabolizing hormone from the kidney.

Medical Faculty of the Charite, Franz Volhard Clinic, HELIOS Klinikum-Berlin, Max Delbruck Center for Molecular Medicine, Berlin, Germany.
Cell Metabolism (Impact Factor: 16.75). 07/2005; 1(6):358-60. DOI: 10.1016/j.cmet.2005.05.008
Source: PubMed

ABSTRACT A novel flavin adenine dinucleotide-dependent amine oxidase that is secreted by the kidney, circulates in the blood, and modulates cardiac function and systemic blood pressure has recently been discovered. Renalase appears to be a hormone that metabolizes catecholamines, and its discovery will facilitate our understanding of sympathetic regulation.

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