Article

A case-control study to examine HLA haplotype associations in patients with posttreatment chronic Lyme disease.

Boston University School of Medicine and Boston Medical Center, Massachusetts 02118, USA.
The Journal of Infectious Diseases (impact factor: 6.41). 10/2005; 192(6):1010-3. DOI:10.1086/432733 pp.1010-3
Source: PubMed

ABSTRACT In a comparison of 95 patients with systemic symptoms that persisted after antibiotic treatment for acute Lyme disease (posttreatment chronic Lyme disease) and 104 control subjects without such symptoms after antibiotic treatment, we sought associations between human leukocyte antigen class II (DRB1 and DQB1) markers and posttreatment chronic Lyme disease. No strong association between posttreatment chronic Lyme disease and any class II allele or genotype was found.

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Keywords

104 control subjects
 
acute Lyme disease
 
antibiotic treatment
 
DQB1
 
genotype
 
human leukocyte antigen class II
 
posttreatment chronic Lyme disease