Utility of myocardial performance index measured by left ventricular catheterization
ABSTRACT Myocardial performance index (MPI) is a valuable index of global ventricular performance. It is almost always measured by Doppler echocardiography. The purposes of this study were (I) to compare MPI measured by catheterization (MPIc) and that measured by Doppler echocardiography (MPId), and (2) to compare it with the functional status.
The study included 80 patients who had undergone left heart catheterization. The MPIc was measured from the pressure recordings obtained at left ventricle and aorta.
Mean MPId and MPIc were 0.40 +/- 0.12 and 0.42 +/- 0.12, respectively. Mean left ventricular end diastolic pressure (LVEDP) was 13 +/- 5 mm Hg. Mean heart rate was 77 +/- 11 beats/min. Mann-Whitney U test revealed that MPIc could discriminate between the functional statuses of the patients. The regression analysis revealed that there is a good correlation between MPIc and MPId, LVEDP or heart rate. There was no significant difference between MPIc and MPId (p > 0.05).
The present data show that (I) the MPIc has a strong correlation with MPId; (2) it is a good discriminator of functional status. It may provide an additional information regarding the left ventricular performance in patients who underwent the cardiac catheterization.
SourceAvailable from: Kun Sun[Show abstract] [Hide abstract]
ABSTRACT: Quantitative assessment of ventricular function in children with single ventricles is both difficult and subjective because of asymmetric ventricular geometry. The Doppler myocardial performance index (MPI) allows the assessment regardless of ventricular shape. This study was designed to evaluate the feasibility of MPI in assessing ventricular function in children with single ventricles before and after total cavopulmonary connection (TCPC). Subjects consisted of 161 pediatric patients with single ventricles and 80 normal children without heart disease. The maximum positive rate of ventricular pressure change (Max dp/dt) was obtained in 58 patients by cardiac catheterization. Sixty-eight children with single ventricles received TCPC. MPI was calculated from Doppler tracings of ventricular inflow and outflow, then MPI of single ventricles before and after surgery and normal heart were compared. Normal MPI value was 0.30+/-0.08 in the left ventricle and 0.26+/-0.08 in the right ventricle. Compared to normal children, MPI was significantly higher in 161 children with single ventricles (0.54+/-0.11, P<0.001). MPI correlated inversely with Max (dp/dt) (r=-0.77, P<0.01), and was positively related to age (r=0.54, P<0.01) in patients with single ventricles. MPI did not differ significantly before and after surgery in 68 patients with single ventricles (0.55+/-0.21 vs 0.51+/-0.20, P>0.05). However, MPI in 48 patients of <6 years old decreased significantly (0.55+/-0.21 vs 0.48+/-0.18, P<0.05), suggesting improved ventricular function. Compared to normal children, ventricular function is impaired in patients with single ventricles and may worsen with age. MPI provides an accurate method for assessing ventricular function in children with single ventricles before and after TCPC.World Journal of Pediatrics 05/2008; 4(2):109-13. DOI:10.1007/s12519-008-0021-y · 1.05 Impact Factor
Article: Kardiyak kateterizasyona ait bas›nç kay›tlar›ndan elde edilen art›rma indeksi ve miyokardiyal performans indeksinin koroner arter hastal›¤›n› öngörme deerleri The value of augmentation index and myocardial performance index obtained from cardiac catheterization pressure recordings in predicting coronary artery disease[Show abstract] [Hide abstract]
ABSTRACT: A Am ma aç ç:: Kalp kateterizasyonu s›ras›nda gerçeklefltirilen bas›nç kay›tlar›ndan elde edilen baz› parametreler ile koroner arter hastal›¤› aras›ndaki iliflkinin saptanmas› amaçland›. Y Yö ön nt te em mlle er r:: Araflt›rmaya dahil kardiyologlar taraf›ndan koroner anjiyografi ve kalp kateterizasyonu uygulanan ard›fl›k 65 hasta çal›flmaya al›nd›, 40'›nda (59±6 y›l; 28 erkek) istenen parametreler elde edildi ve bu hastalar istatistiksel analize dahil edildi. Bas›nç kay›tlar›ndan miyokardiyal performans indeksi (MP‹), izovolümetrik relaksasyon zaman› (‹VRZ), izovolümetrik kontraksiyon zaman› (‹VKZ), ejeksiyon zaman› (EZ), art›rma dalga yükseklii (ADY), art›rma dalga zaman› (ADZ) ve art›rma indeksi (A‹) elle ölçüldü. Koroner arter hastal›¤›, herhangi bir koroner arterde, darl›k derecesine bak›lmaks›z›n, lezyon varl›¤› olarak tan›mland›. Elde edilen parametrelerin koroner arter hastal›¤› varl›¤› ile iliflkileri (Mann-Whitney U testi), ateroskleroz risk etmenleriyle iliflkileri (Mann-Whitney U testi ve ki kare testi), koroner arter hastal›¤›n› öngörme yetisi (ROC erisi alt›nda kalan alan, AUC) araflt›r›ld›. ‹statistiksel anlaml›l›k s›n›r› 0.05 kabul edildi. B Bu ullg gu ulla ar r:: Koroner arter hastal›¤› varl›¤› ile A‹, ADY, ADZ, ‹VRZ ve MP‹ iliflkili bulundu. (tümü için p