Article
Synthesis and antifungal activity of oxygenated cholesterol derivatives.
Laboratoire Synthèse et Etude de Substances Naturelles à Activités Biologiques (SESNAB), IMRN INRA 1111, Faculté des Sciences et Techniques de St Jérôme, Université Paul Cézanne, Aix-Marseille III, 13397 Marseille Cedex 20, France.
Steroids (impact factor:
2.83).
01/2006;
70(13):907-12.
DOI:10.1016/j.steroids.2005.06.007
pp.907-12
Source: PubMed
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Citations (0)
- Cited In (1)
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Article: Synthesis and preliminary biological screening of sterol analogues as new antifungal agents against plant pathogens.
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ABSTRACT: In this paper we report the synthesis of a new family of sterol analogues that have two amidic bonds on the side chain. These azasterols were obtained by a straightforward procedure including an Ugi condensation that allows the facile attachment of a polyfunctionalized side chain into the steroidal framework. Some of the new compounds showed an interesting inhibitory effect on the growth of two pathogenic fungi involved in plant diseases.Steroids 10/2010; 75(10):659-64. · 2.83 Impact Factor
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Keywords
different compounds
diketone 7
miconazole resistant strain C. albicans
new synthetic methods
oxygenated cholesterol derivatives
S. cerevisiae
vitro antimicrobial properties
