An Epidemiologic Study of Irritable Bowel Syndrome in Adolescents and Children in China: A School-Based Study Liu Dong, Li Dingguo, Xu Xiaoxing and Lu Hanming Pediatrics 2005;116;e393 DOI: 10.1542/peds.2004-2764

Shanghai Medical University, Shanghai, Shanghai Shi, China
PEDIATRICS (Impact Factor: 5.47). 10/2005; 116(3):e393-6. DOI: 10.1542/peds.2004-2764
Source: PubMed


To explore the prevalence of irritable bowel syndrome (IBS) and its distribution characteristics of adolescents and children in China and its contributing factors.
This study was a stratified, randomized study by clustering samples, which involved 5403 students whose age range was 6 to 18 years from 9 schools, and was conducted in Heilongjiang Province and Shanghai. All students studied were requested to fill in a questionnaire. IBS was diagnosed according to Rome II criteria.
The prevalence of IBS according to Rome II criteria in adolescents and children in China was 13.25%. The ratio of boys to girls was 1:1.8. There was a higher prevalence (14.02%) of IBS in Heilongjiang province than that (11.72%) in Shanghai. The prevalence in children 12 years and younger was not statistically significantly higher than that of adolescents 13 years and older (11.86% and 11.44%, respectively). The prevalence of IBS in minority students (21.15%) was not statistically significantly higher than that in Han race students (16.08%). Our study indicated that psychological factors, food habit, bad exterior environment, personal habits, and family conditions might be important contributing factors, and exposure to coldness (odds ratio: 2.83) is most prominent.
IBS was a common disorder in adolescents and children in China. The prevalence of IBS in adolescents and children was different in different geographic areas. Our study indicated that IBS in adolescents and children might have possible relations with psychological factors, food habit, bad exterior environment, and family condition.

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    • "Walker et al. [18] reported recurrent abdominal pain as the common symptom in 44.9% of children with IBS. The prevalence of IBS in teenagers and children varied between Shanghai and Heilongjiang, 11.72% in Shanghai and 14.02% in Heilongjiang [19–21]. A large-scale epidemiologic survey of IBS in children either abroad or from China is lacking. "
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    ABSTRACT: To determine the prevalence and risk factors of IBS in children 8-13 years of age in Suzhou city, a cross-sectional study was conducted on children in grades 1 through 6 in public elementary schools in three districts of Suzhou. A multistage stratified random-sampling survey was conducted in a primary investigation using standardized questionnaires. Rome II criteria were used to confirm IBS and their risk factors were analyzed. Of 8,000 questionnaires 7,472 responded satisfactorily for a response rate of 93.4%. IBS was diagnosed in 10.81%. A decrease in the prevalence of IBS was significantly associated with advancing age and grade in school (trend test, P < 0.05). The prevalence of IBS in females was higher but not significantly different than males. The significant risk factors for IBS included young age (OR = 0.94), food allergy (OR = 1.53), gastroenteritis during childhood (OR = 1.29), eating fried food (OR = 1.62), anxiety (OR = 1.49), psychological insults in early childhood (OR = 1.47), and parental history of constipation (OR = 1.81; all P < 0.05). IBS prevalence of 10.81% in study population warrants preventive measures such as encouraging dietary changes, preventing gastroenteritis and childhood psychological insults.
    Gastroenterology Research and Practice 05/2014; 2014(7):198461. DOI:10.1155/2014/198461 · 1.75 Impact Factor
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    • "Previous study conducted in Sri Lankan children has reported organic disorders in 11% of children with recurrent abdominal pain.7 We expect a similar percentage of organic disorders in this group of children. Nonetheless, most of the previous epidemiological studies done among adults and children have used a similar methodology.2,3,20,30,35-37 "
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    ABSTRACT: This study was conducted with objectives of assessing subtypes of irritable bowel syndrome (IBS) in children aged 10-16 years, their symptomatology and gender differences. For this survey, 107 children who fulfilled Rome III criteria for IBS and 1,610 healthy controls were recruited from 8 randomly selected schools, in 4 provinces in Sri Lanka. Data was collected using a previously validated, self administered questionnaire. Constipation predominant, diarrhea predominant and mixed type IBS were almost equally distributed (27%-28%), while unsubtyped IBS had a lower prevalence (17.8%). IBS was more common in girls (59.8% vs 40.2% in boys, P = 0.001). Bloating, flatulence, burping, headache and limb pain were significantly higher in affected children (P < 0.05). This study highlights the distribution of IBS subtypes among Sri Lankan children and adolescents and its female preponderance. This study also shows a higher prevalence of other intestinal-related and extraintestinal somatic symptoms among affected children.
    Journal of neurogastroenterology and motility 07/2012; 18(3):298-304. DOI:10.5056/jnm.2012.18.3.298 · 2.30 Impact Factor
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    • "Generally, race,5 gender,6-9 age,10-12 marital status,13,14 stress,6-8,13-16 food,11,14,17-19 or alcohol and tobacco use11 have been considered as risk factors to IBS. In particular, the food or nutritional intake has been estimated to be closely associated with the pathophysiology of IBS.19 Several IBS studies have been performed since the publication of the Rome III criteria in 2006.1,4,20-22 "
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    ABSTRACT: Irritable bowel syndrome (IBS) is prevalent in general population. This study investigates the prevalence of IBS in medical college students in Korea as well as the influence of dietary habits and nutritional intake on IBS. This study is a cross-sectional study of 319 students (239 males and 80 females, age 22.3 ± 2.5 years) from the 6 grade levels of the Medical College in Korea. All students filled out a self-reported questionnaire for ROME III criteria. They also completed a questionnaire to validate dietary habits and food frequency in Korean. The overall prevalence of IBS was 29.2% without correlation to age, body mass index and grade level in Medical School. However, the prevalence was significantly higher in females than males (33/80 vs 60/239, P = 0.007). There were no significant differences between the IBS-group and the non-IBS group in aspect of nutrition. Not only the diet habits, but also the daily nutritional intake, and even the breakdown into the 12 micronutrients, yielded no significant differences between the 2 groups. Twenty-nine percent of the medical college students have IBS with a greater prevalence in females. The dietary habits and nutritional intake of the students might not be associated with IBS.
    Journal of neurogastroenterology and motility 07/2011; 17(3):294-9. DOI:10.5056/jnm.2011.17.3.294 · 2.30 Impact Factor
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