Bloody nipple discharge in infants

East Sussex Healthcare NHS Trust, Eastbourne, England, United Kingdom
The Breast (Impact Factor: 2.38). 05/2006; 15(2):253-4. DOI: 10.1016/j.breast.2005.05.004
Source: PubMed


Though milky nipple discharge is frequently seen in neonates, blood stained discharge from the nipple is an exceptionally rare phenomenon. We noted a case of a three-month-old baby girl who presented with bilateral blood stained nipple discharge without signs of inflammation; engorgement or hypertrophy and which subsided without any intervention. This case is reported along with literature review about managing this rare condition.

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    • "M 28 mo L 1 mo Normal Dilated mammary duct in retroareolar region of left breast No intervention MDE 1 mo Neg Foam cells, rarely ductal epithelial cells; no atypical cells Prolactin, estradiol, testosterone, and gonadotropin serum levels were normal 21 Kelly 2006 [7] M 4 mo Bil 2 mo Normal No intervention 1 mo Neg Normal Prolactin and estradiol levels were normal 22 George and Donnelly 2006 [31] F 3 mo Bil 2 wk Normal No antibiotic treatment 1 mo (left), 7 mo (right) Neg Benign 23 Schwartz et al. 2006 [21] "
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    ABSTRACT: Background/purpose: Bloody nipple discharge (BND) is rare, distressing for parents, and presents a challenge for physicians. Methods: We used PubMed to search for cases of BND that were diagnosed before adolescence and added data from two of our cases. Results: The analyzed cohort comprised 46 patients (28 boys and 18 girls; mean [SD] age, 12.5±13.3months; range, 20days to 4years). The mean time for spontaneous resolution was 2.8±2.4months (range, 1week to 8months) after onset of BND without any intervention. The diagnosis was mammary ductal ectasia (MDE) in 15 patients, gynecomastia with MDE in two patients, hemorrhagic cysts in two patients, and gynecomastia alone in one patient. The majority (89.3%) of patients <1year old were managed conservatively, but half of them aged >1year (50.0%) underwent surgery. Surgery was performed more often in patients in whom a mass had been identified. Conclusions: Age and findings at physical examination affect selection of treatment, but not sex. We found no reported cases of malignancy. Symptoms in children who are managed conservatively resolve within 10months. Children with BND should be conservatively managed to avoid the risk of developing breast deformities before adolescence.
    Journal of Pediatric Surgery 09/2015; DOI:10.1016/j.jpedsurg.2015.08.049 · 1.39 Impact Factor
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    • "Kelly et al14) mentioned a diagnostic approach to the evaluation of bloody nipple discharges in infants. In an infant apparently experiencing bloody nipple discharge, the initial workup should include a Gram-stain; cell count and culture of the discharge; serum levels of prolactin, estradiol, and thyrotropin; and an ultrasound of the affected breast. "
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    ABSTRACT: Although milky nipple discharge appears frequently in infants, bloody nipple discharge is a very rare finding. We experienced a 4-month-old, breast-fed infant who showed bilateral bloody nipple discharge with no signs of infection, engorgement, or hypertrophy. The infant's hormonal examination and coagulation tests were normal, and an ultrasound examination revealed mammary duct ectasia. The symptoms resolved spontaneously within 6 weeks without any specific treatment, except that we advised the mother to refrain from taking herbal medicine. Since no such case has been previously reported in Korea, we present this case with a brief review of the literature.
    Korean Journal of Pediatrics 10/2010; 53(10):917-20. DOI:10.3345/kjp.2010.53.10.917
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    Intelligent Processing Systems, 1997. ICIPS '97. 1997 IEEE International Conference on; 11/1997
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