[Cardiac papillary fibroelastoma. Experience of an institution].

Instituto do Coração, Hospital das Clínicas, FMUSP, São Paulo, SP.
Arquivos Brasileiros de Cardiologia (Impact Factor: 1.12). 10/2005; 85(3):205-7. DOI: 10.1590/S0066-782X2005001600010
Source: PubMed

ABSTRACT Primary intracardiac tumors are rare, with prevalence between 0.0017% and 0.19% from non-selected autopsy studies. Approximately 75% are benign and almost half of them are myxomas. The remaining tumors are divided among rhabdomyomas, lipomas and fibroelastomas. Myxomas are the most common intracardiac tumors in adult age and rhabdomyomas the most common among pediatric population. Papillary fibroelastoma (PFE) is a relative rare benign heart tumor, corresponding to approximately 8% of intracardiac tumors. They most commonly manifested in cardiac valves. In the past, they either consisted of necropsy findings or were found in surgical procedures at random. In vivo diagnosis was sporadic. With the improvement of echocardiography techniques, PFE has been more frequently diagnosed. They are usually described as a movable, pedunculate, well-delimited mass and with predilection for valve endocardium. Therapeutic proposal, when they are pedunculate, is surgical resection, preventing cerebral, pulmonary, coronary or peripheral embolic phenomena. Five cases diagnosed in our institution, in the period from August 1995 to June 2004, will be presented.

  • [Show abstract] [Hide abstract]
    ABSTRACT: Cardiac papillary fibroelastomas (PFEs), which are mainly found in the valves, are rare benign tumors that can cause embolism. Single-center surgical experience in the treatment of this tumor is uncommon. All patients surgically treated for this neoplasm at our institution from January 1995 to October 2012 (15 patients with 17 lesions) were queried for clinical and pathologic characteristics, and the literature was reviewed. The mean age of detection was 55.8±11.48 years. Twenty percent of the patients were male. The tumor was an incidental finding in 60%. Symptoms directly related to PFEs occurred in 40% of patients. The most common clinical presentation in symptomatic cases was embolism (40%), mostly transient ischemic attack or stroke. Cardiac valves were predominantly involved (76.5%); the most commonly valve affected was the aortic valve (29.4%), followed by the mitral valve (17.6%). Concurrent valvular disease was observed in 41.7% of patients. The mean size of tumors was 11.4±7.9mm (range 2-25mm). In 86.7% of the patients, the tumor was solitary. The mitral valve was the most common origin of tumor systemic embolism. Fronds core could be the end stage of hypermature elastic fibers, which grows in apposition to young fibers. Simple surgical excision or valvular reconstruction was accomplished in most patients (58.3%). PFE is usually small, appears singly, and can cause potentially serious complications. Symptomatic and left side tumors should undergo surgical excision with valve-spare surgery when possible. Surgical removal of PFE is safe, efficacious, and definitive.
    Pathology - Research and Practice 02/2013; 209(4). DOI:10.1016/j.prp.2013.02.001 · 1.56 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Cardiac papillary fibroelastoma is a rare benign tumor of the heart mostly involving the valves or left sided chambers. It is often diagnosed during evaluation for other pathologies. It may produce symptoms due to its location or embolisation of the tumor itself or superimposed thrombus. It is therefore advisable to excise this tumor to prevent the catastrophic effects of systemic, pulmonary or paradoxical embolism.
    Indian Journal of Thoracic and Cardiovascular Surgery 07/2006; 22(3):188-190. DOI:10.1007/s12055-006-0756-9
  • [Show abstract] [Hide abstract]
    ABSTRACT: A patient with Turner syndrome presented with shortness of breath with exertion. Three-dimensional transesophageal echocardiogram revealed bicuspid aortic valve with severe aortic stenosis. There were multiple masses attached to the aortic valve and tricuspid valve, which mimicked vegetations. Patient underwent aortic and tricuspid valve replacement. Histology revealed papillary fibroelastomas of the aortic valve and tricuspid valve. This is the first report of papillary fibroelastomas involving both the left and the right-sided valves in a patient with Turner syndrome.
    The Canadian journal of cardiology 10/2014; 30(10). DOI:10.1016/j.cjca.2014.05.014 · 3.12 Impact Factor

Full-text (2 Sources)

Available from
Dec 8, 2014