Management of Newly Diagnosed HIV Infection

Division of Infectious Diseases, Columbia University Medical Center, New York 10032, USA.
New England Journal of Medicine (Impact Factor: 55.87). 11/2005; 353(16):1702-10. DOI: 10.1056/NEJMcp051203
Source: PubMed


As part of a routine examination for insurance coverage, a 25-year-old previously healthy woman is found to have a positive test for human immunodeficiency virus type 1 (HIV-1) antibody. Heterosexual contact is her only risk factor for HIV acquisition. She is asymptomatic and has a normal physical examination. The results of hematologic and other routine laboratory tests are normal. Her CD4 cell count is 325 cells per cubic millimeter, and her plasma HIV-1 RNA level is 60,000 copies per milliliter (both confirmed on repeated testing). How should her case be managed?

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