Fluoroquinolone-resistant Vibrio cholerae isolated during a cholera outbreak in India.

Department of Microbiology, Karnataka Institute of Medical Sciences, Hubli 580022, India.
Transactions of the Royal Society of Tropical Medicine and Hygiene (Impact Factor: 1.93). 04/2006; 100(3):224-6. DOI: 10.1016/j.trstmh.2005.07.007
Source: PubMed

ABSTRACT During the cholera epidemic of 2002 in and around Hubli, south India, Vibrio cholerae strains resistant to fluoroquinolones were isolated. Among the isolates of V. cholerae non-O1, non-O139 serogroups, 55.9% and 47.1% were resistant to norfloxacin and ciprofloxacin, respectively. However, only 12.5% of the O1 serogroup strains were resistant to both norfloxacin and ciprofloxacin. Though the O139 serogroup strains were susceptible to these antibiotics, they exhibited multidrug resistance. Emergence of fluoroquinolone-resistant V. cholerae that also exhibited multidrug resistance is of great significance in the epidemiology and control of cholera.

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